Belenky Nadya, Pence Brian W, Cole Stephen R, Dusetzina Stacie B, Edmonds Andrew, Oberlander Jonathan, Plankey Michael, Adedimeji Adebola, Wilson Tracey E, Cohen Jennifer, Cohen Mardge H, Milam Joel E, Adimora Adaora A
a Division of Infectious Diseases, School of Medicine , The University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
b Department of Epidemiology, Gillings School of Global Public Health , The University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
AIDS Care. 2019 Apr;31(4):505-512. doi: 10.1080/09540121.2018.1516283. Epub 2018 Sep 6.
Depression is common among women with HIV and untreated depression can result in poor quality of life and worsen HIV outcomes. Women with HIV who are dually enrolled in Medicaid and Medicare faced a potential disruption in medication access when Medicare Part D was implemented in 2006. The goal of this study was to estimate the effects of Medicare Part D implementation on antidepressant use, depressive symptoms, and hospitalization in Medicaid-Medicare dual eligible women with HIV. This study used 2003-2008 data from the Women's Interagency HIV Study. The effects of Medicare Part D were estimated using a difference-in-differences approach, adjusting for temporal trends using a matched control group of Medicaid-only enrollees. Before Medicare Part D implementation, dual eligibles differed from Medicaid-only enrollees in antidepressant use and hospitalization, despite having identical prescription drug coverage through Medicaid. For dual enrollees, the transition to Medicare Part D was not associated with changes in antidepressant use, depressive symptoms, or hospitalization. We did not find disruptive effects on antidepressant use and related outcomes among dual eligibles in this study. Stable antidepressant use may be due to better access to medical care for dual eligibles through Medicare both before and after Medicare Part D implementation, which may have eclipsed any effects of the transition. It may also signal that classification of antidepressants as a protected drug class under Medicare Part D was effective in preventing psychiatric medication disruption.
抑郁症在感染艾滋病毒的女性中很常见,未经治疗的抑郁症会导致生活质量下降,并使艾滋病毒感染情况恶化。同时参加医疗补助计划和医疗保险的感染艾滋病毒的女性在2006年医疗保险D部分实施时面临药物获取方面的潜在中断。本研究的目的是评估医疗保险D部分的实施对同时符合医疗补助计划和医疗保险资格的感染艾滋病毒女性的抗抑郁药物使用、抑郁症状和住院情况的影响。本研究使用了妇女机构间艾滋病毒研究2003 - 2008年的数据。医疗保险D部分的影响采用差异中的差异方法进行评估,并使用仅参加医疗补助计划的匹配对照组来调整时间趋势。在医疗保险D部分实施之前,尽管通过医疗补助计划拥有相同的处方药覆盖范围,但同时符合两项资格者在抗抑郁药物使用和住院方面与仅参加医疗补助计划者存在差异。对于同时参加两项计划者而言,向医疗保险D部分的过渡与抗抑郁药物使用、抑郁症状或住院情况的变化无关。在本研究中,我们未发现对同时符合两项资格者的抗抑郁药物使用及相关结果有干扰作用。抗抑郁药物使用稳定可能是由于在医疗保险D部分实施前后,同时符合两项资格者通过医疗保险能更好地获得医疗服务,这可能掩盖了过渡带来的任何影响。这也可能表明,在医疗保险D部分下将抗抑郁药物归类为受保护药物类别在预防精神科药物中断方面是有效的。