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疑似莱姆病患者的多学科管理。

Multidisciplinary management of patients presenting with Lyme disease suspicion.

机构信息

Service de maladies infectieuses et tropicales, CHRU de Nancy, rue du Morvan, 54500 Vandoeuvre-les-Nancy, France.

Service de maladies infectieuses et tropicales, CHRU de Nancy, rue du Morvan, 54500 Vandoeuvre-les-Nancy, France.

出版信息

Med Mal Infect. 2019 Mar;49(2):112-120. doi: 10.1016/j.medmal.2018.06.002. Epub 2018 Sep 3.

Abstract

OBJECTIVE

The teaching hospital of Nancy, France, implemented a specific multidisciplinary care pathway (French acronym AMDPL) to improve the management of patients presenting with Lyme borreliosis (LB) suspicion. We aimed to assess the first year of activity of this care pathway.

PATIENTS AND METHODS

We included all patients managed in the AMDPL pathway from November 1, 2016 to October 31, 2017. The first step was a dedicated Lyme disease consultation with an infectious disease specialist. Following this consultation, the LB diagnosis was either confirmed and adequate treatment was prescribed, or a differential diagnosis was established and patients received adequate management, or further investigations were required and patients were offered multidisciplinary management as part of a day hospitalization.

RESULTS

A total of 468 patients were included. LB diagnosis was confirmed in 15% of patients (69/468), 49% of patients received a differential diagnosis, and 26% (122/468) of patients had the LB diagnosis ruled out without receiving any other diagnosis.

CONCLUSIONS

This is to our knowledge the first multidisciplinary center implemented in France for the management of patients presenting with LB suspicion related to polymorphous signs and symptoms. Several diagnoses could be confirmed or corrected, although some symptoms and complaints could not be explained. This cohort could improve our knowledge of LB and its differential diagnoses.

摘要

目的

法国南锡教学医院实施了一种特定的多学科护理路径(法语缩写为 AMDPL),以改善疑似莱姆病(LB)患者的管理。我们旨在评估该护理路径实施的第一年的活动情况。

患者和方法

我们纳入了 2016 年 11 月 1 日至 2017 年 10 月 31 日期间在 AMDPL 路径中接受管理的所有患者。第一步是由传染病专家进行专门的莱姆病咨询。在这次咨询之后,如果 LB 诊断得到确认并开出了适当的治疗方法,则完成诊疗;如果建立了鉴别诊断,则为患者提供适当的管理;如果需要进一步的检查,则为患者提供多学科管理,作为日间住院的一部分。

结果

共纳入 468 例患者。15%的患者(69/468)的 LB 诊断得到确认,49%的患者进行了鉴别诊断,26%(122/468)的患者排除了 LB 诊断而没有接受任何其他诊断。

结论

据我们所知,这是法国第一个为管理具有多态性体征和症状的疑似 LB 患者而实施的多学科中心。尽管有些症状和主诉无法解释,但可以确认或纠正几个诊断。该队列可以提高我们对 LB 及其鉴别诊断的认识。

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