Kan Charlene E, Mansur David B
Department of Radiation Oncology, Case Western Reserve University School of Medicine, University Hospitals, Seidman Cancer Center, 11100 Euclid Avenue, Lerner Tower B-141, Cleveland, OH 44106, USA.
Melanoma Manag. 2016 Mar;3(1):61-72. doi: 10.2217/mmt.15.41. Epub 2016 Feb 24.
The local treatment of cutaneous melanoma with surgical excision is well-established; however, the role of adjuvant radiation is not well-defined. Characteristics of the primary melanoma can indicate a higher local recurrence risk and thus warrant consideration of adjuvant treatment to the primary site. Management of the lymph node regions has been studied in some recent clinical trials, especially with the advent of sentinel lymph node procedures. We will review the indications for radiation to the primary site as well as lymph node regions based on the available data.
手术切除对皮肤黑色素瘤进行局部治疗已得到广泛认可；然而，辅助放疗的作用尚不明确。原发性黑色素瘤的特征可提示较高的局部复发风险，因此有必要考虑对原发部位进行辅助治疗。最近的一些临床试验对淋巴结区域的处理进行了研究，尤其是在前哨淋巴结手术出现之后。我们将根据现有数据回顾对原发部位以及淋巴结区域进行放疗的适应证。
