Enrich C, Bachs O, Soriano M, Serratosa J
Biochim Biophys Acta. 1986 Oct 9;861(2):381-4. doi: 10.1016/0005-2736(86)90443-8.
Changes in a range of plasma membrane enzyme activities during the early period of liver regeneration are thought to be related to the initiation of DNA synthesis and the triggering of cellular activation. The sinusoidal plasma membrane was isolated from control and partially hepatectomized animals at various intervals during the pre-replicative phase. The specific activities of 5'-nucleotidase, (Na+ + K+)-ATPase, Ca2+-ATPase, Mg2+-ATPase showed that after partial hepatectomy changes in the enzyme activities at the sinusoidal plasma membrane region occur. These changes are probably related to the remodeling of the cell-surface that occurs before the division of hepatocytes.
肝脏再生早期一系列质膜酶活性的变化被认为与DNA合成的起始以及细胞激活的触发有关。在复制前期的不同时间间隔，从对照动物和部分肝切除的动物中分离出肝血窦质膜。5'-核苷酸酶、（钠+钾）-ATP酶、钙-ATP酶、镁-ATP酶的比活性表明，部分肝切除后，肝血窦质膜区域的酶活性发生了变化。这些变化可能与肝细胞分裂前发生的细胞表面重塑有关。
