1Action & Cognition Laboratory,Institute of Psychology,Faculty of Social Sciences,Adam Mickiewicz University in Poznań,Poland.
2Section of Logic and Cognitive Science,Institute of Psychology,Faculty of Social Sciences,Adam Mickiewicz University in Poznań,Poland.
J Int Neuropsychol Soc. 2018 Nov;24(10):1013-1025. doi: 10.1017/S1355617718000590. Epub 2018 Sep 10.
We used multivoxel pattern analysis (MVPA) to investigate neural selectivity for grasp planning within the left-lateralized temporo-parieto-frontal network of areas (praxis representation network, PRN) typically associated with tool-related actions, as studied with traditional neuroimaging contrasts.
We used data from 20 participants whose task was to plan functional grasps of tools, with either right or left hands. Region of interest and whole-brain searchlight analyses were performed to show task-related neural patterns.
MVPA revealed significant contributions to functional grasp planning from the anterior intraparietal sulcus (aIPS) and its immediate vicinities, supplemented by inputs from posterior subdivisions of IPS, and the ventral lateral occipital complex (vLOC). Moreover, greater local selectivity was demonstrated in areas near the superior parieto-occipital cortex and dorsal premotor cortex, putatively forming the dorso-dorsal stream.
A contribution from aIPS, consistent with its role in prospective grasp formation and/or encoding of relevant tool properties (e.g., potential graspable parts), is likely to accompany the retrieval of manipulation and/or mechanical knowledge subserved by the supramarginal gyrus for achieving action goals. An involvement of vLOC indicates that MVPA is particularly sensitive to coding of object properties, their identities and even functions, for a support of grip formation. Finally, the engagement of the superior parieto-frontal regions as revealed by MVPA is consistent with their selectivity for transient features of tools (i.e., variable affordances) for anticipatory hand postures. These outcomes support the notion that, compared to traditional approaches, MVPA can reveal more fine-grained patterns of neural activity. (JINS, 2018, 24, 1013-1025).
我们使用多体素模式分析（MVPA）来研究与工具相关动作相关的左侧颞顶额区域（动作表现网络，PRN）内的抓握规划的神经选择性，如使用传统的神经影像学对比进行研究。
我们使用了 20 名参与者的数据，他们的任务是用右手或左手规划功能性工具抓握。进行了感兴趣区域和全脑搜索光分析，以显示与任务相关的神经模式。
MVPA 显示，前内顶叶回（aIPS）及其附近区域对功能性抓握规划有显著贡献，由 IPS 的后部分支和腹外侧枕叶复合体（vLOC）补充。此外，在靠近顶枕上回和背侧运动前皮质的区域显示出更大的局部选择性，可能形成背-背流。
aIPS 的贡献与其在预期抓握形成和/或编码相关工具属性（例如潜在可抓握部分）的作用一致，可能伴随着由缘上回检索用于实现动作目标的操作和/或机械知识。vLOC 的参与表明 MVPA 特别敏感于对象属性的编码，其身份甚至功能，以支持握力形成。最后，MVPA 揭示的顶枕额区域的参与与它们对工具瞬态特征（即可变的可及性）的选择性一致，以预测手姿势。这些结果支持了这样的观点，即与传统方法相比，MVPA 可以揭示更精细的神经活动模式。（JINS，2018，24，1013-1025）。
