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恶性外耳道炎:一项回顾性分析及治疗结果

Malignant Otitis Externa: A Retrospective Analysis and Treatment Outcomes.

作者信息

Kaya İsa, Sezgin Baha, Eraslan Sevinç, Öztürk Kerem, Göde Sercan, Bilgen Cem, Kirazlı Tayfun

机构信息

Department of Otorhinolaryngology, Ege University School of Medicine, İzmir, Turkey.

出版信息

Turk Arch Otorhinolaryngol. 2018 Jun;56(2):106-110. doi: 10.5152/tao.2018.3075. Epub 2018 Jun 1.

Abstract

OBJECTIVE

The purpose of this study was to analyze previous treatments and outcomes in patients with malignant otitis externa (MOE) retrospectively. The efficacy of medical and surgical treatments was also evaluated.

METHODS

This study included 25 patients diagnosed with MOE and treated at the Department of Otorhinolaryngology, Ege University School of Medicine between 2006 and 2017. The duration of hospitalization, Hemoglobin A1c (HbA1c) levels of the patients, erythrocyte sedimentation rate (ESR), source of the infection, complications, and previous medical and surgical treatments were also retrospectively assessed.

RESULTS

The mean age of the patients (7 females and 18 males) was 69.68±11.29 years. The mean length of hospital stay in patients with HbA1c levels ≤6 and in patients with HbA1c levels >6 was 26.86 and 33.39 days, respectively. The mean hospitalization time was significantly longer in patients with HbA1c levels >6 (p<0.05). Additionally, elderly patients (age>65 years) had a significantly longer hospital stay in our study (p<0.05). ESR was found to be 52.76±32.49 (9-108) mm/h at the first examination and 14.92±1.22 (4-32) mm/h at the time of discharge.

CONCLUSION

MOE is an aggressive disease that requires conservative management, and ESR proved to be a good indicator of treatment response. Long-term antibiotherapy are recommended for treatment.

摘要

目的

本研究旨在回顾性分析恶性外耳道炎(MOE)患者既往的治疗情况及预后。同时评估内科和外科治疗的疗效。

方法

本研究纳入了2006年至2017年间在伊兹密尔埃杰大学医学院耳鼻喉科诊断并治疗的25例MOE患者。还回顾性评估了患者的住院时间、糖化血红蛋白(HbA1c)水平、红细胞沉降率(ESR)、感染源、并发症以及既往的内科和外科治疗情况。

结果

患者(7例女性和18例男性)的平均年龄为69.68±11.29岁。HbA1c水平≤6的患者和HbA1c水平>6的患者的平均住院时间分别为26.86天和33.39天。HbA1c水平>6的患者平均住院时间显著更长(p<0.05)。此外,在我们的研究中,老年患者(年龄>65岁)的住院时间显著更长(p<0.05)。首次检查时ESR为52.76±32.49(9 - 108)mm/h,出院时为14.92±1.22(4 - 32)mm/h。

结论

MOE是一种侵袭性疾病,需要保守治疗,ESR被证明是治疗反应的良好指标。建议长期使用抗生素治疗。

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