Goodman G B, Lam G K, Harrison R W, Bergstrom M, Martin W R, Pate B D
Int J Radiat Oncol Biol Phys. 1986 Oct;12(10):1867-71. doi: 10.1016/0360-3016(86)90332-9.
The radioactive debris produced by pion radiotherapy can be imaged by the technique of Positron Emission Tomography (PET) as a method of non-invasive in situ verification of the pion treatment. This paper presents the first visualization of the pion stopping distribution within a tumor in a human brain using PET. Together with the tissue functional information provided by the standard PET scans using radiopharmaceuticals, the combination of pion with PET technique can provide a much better form of radiotherapy than the use of conventional radiation in both treatment planning and verification.
π介子放射疗法产生的放射性碎片可以通过正电子发射断层扫描（PET）技术进行成像，作为一种对π介子治疗进行非侵入性原位验证的方法。本文展示了利用PET对人脑肿瘤内π介子的停止分布进行的首次可视化。结合使用放射性药物进行的标准PET扫描所提供的组织功能信息，π介子与PET技术相结合，在治疗计划和验证方面都能提供比传统放疗更好的放射治疗形式。
