在系统性镰刀菌病的体内小鼠模型中，细胞外容积（ECV）与预后缺乏相关性。
Lack of correlation of ECV and outcome in an in vivo murine model of systemic fusariosis.
作者信息
Navarro-Rodríguez Patricia, Guevara-Suarez Marcela, Paredes Katihuska, Celis Adriana, Guarro Josep, Capilla Javier
机构信息
Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Tarragona, Spain.
Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Tarragona, Spain; Laboratorio de Micología y Fitopatología, Departamento de Ciencias Biológicas, Universidad de Los Andes, Bogotá, Colombia.
出版信息
Diagn Microbiol Infect Dis. 2018 Oct;92(2):124-126. doi: 10.1016/j.diagmicrobio.2018.05.019. Epub 2018 May 29.
The efficacy of liposomal amphotericin B and voriconazole was evaluated against the systemic infection by Fusarium oxysporum species complex or Fusarium keratoplasticum. Although MIC values were within the epidemiological cutoff values (ECVs) recently stablished for Fusarium spp., no efficacy was obtained, indicating that ECVs for Fusarium are not relevant for in vivo efficacy.
评估了脂质体两性霉素B和伏立康唑对尖孢镰刀菌复合种或角膜镰刀菌引起的全身感染的疗效。尽管最低抑菌浓度（MIC）值在最近为镰刀菌属确定的流行病学临界值（ECV）范围内，但未获得疗效，这表明镰刀菌的ECV与体内疗效无关。
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