Pulmonary and Critical Care, Johns Hopkins Hospital and Health System, Baltimore, MD.
Internal Medicine, Cleveland Clinic, Cleveland, OH.
Chest. 2019 Jan;155(1):178-193. doi: 10.1016/j.chest.2018.08.1060. Epub 2018 Sep 7.
Lung transplant is now an established modality for a broad spectrum of end-stage pulmonary diseases. According to the International Society for Heart and Lung Transplantation Registry, more than 50,000 lung transplants have been performed worldwide, with nearly 11,000 recipients of lung transplants alive in the United States. With the increasing use of lung transplant, pulmonologists must be cognizant of the common as well as the unique posttransplant dermatologic complications. Immunosuppression, infections, and a variety of medications and environmental exposures can contribute to these complications. This review aims to provide representative pictures and describe the pathogenesis, epidemiologic characteristics, and clinical manifestations of dermatologic complications encountered among recipients of lung transplants.
肺移植现已成为广泛终末期肺部疾病的一种成熟治疗手段。根据国际心肺移植学会的注册数据，全世界已经完成了超过 5 万例肺移植，其中近 11000 例在美国的肺移植受者仍然存活。随着肺移植的应用日益增多，肺科医生必须认识到肺移植后常见和独特的皮肤并发症。免疫抑制、感染以及各种药物和环境暴露都可能导致这些并发症。本综述旨在提供有代表性的图片，并描述肺移植受者中遇到的皮肤科并发症的发病机制、流行病学特征和临床表现。
