Department of Neurosurgery, Cantonal Hospital of Fribourg, Fribourg, Switzerland.
Pathology institute Promed, Fribourg, Switzerland.
Neurosurgery. 2019 Mar 1;84(3):E211-E214. doi: 10.1093/neuros/nyy080.
Cavernous angiomas or cavernomas are vascular malformations usually located in the brain parenchyma. However, they rarely present as extra-axial lesions, attached to the dura, and may mimic meningiomas. Most reported cases concern the cavernous sinus region and other locations are very uncommon.
A 61-yr-old female known for long-standing mental illness presented with progressive gait instability. Imaging studies revealed an extra-axial lesion in relation to the anterior part of the falx cerebri. An interhemispheric approach was used to remove the lesion. Pathological analysis revealed features compatible with an extra-axial cavernoma: structureless vascular channels lacking smooth muscle and elastic lamellae, without intervening brain parenchyma.
Cavernous angiomas or cavernomas can present as extra-axial lesions. Although progressive growth can be observed, they should not be considered as tumoral lesions, because there is no cellular duplication. Unlike other locations, resection of anterior cranial fossa extra-axial cavernomas seems to be facilitated by minimal bleeding.
海绵状血管瘤或海绵状血管畸形通常位于脑实质内。然而,它们很少表现为与硬脑膜相连的颅外病变,可能类似于脑膜瘤。大多数报道的病例涉及海绵窦区域,其他部位非常罕见。
一名 61 岁女性,长期患有精神疾病,出现进行性步态不稳。影像学研究显示额镰前部存在颅外病变。采用大脑半球间入路切除病变。病理分析显示符合颅外海绵状血管瘤的特征:无结构的血管通道,缺乏平滑肌和弹性层,没有脑实质介入。
海绵状血管瘤或海绵状血管畸形可表现为颅外病变。虽然可以观察到进行性生长,但不应将其视为肿瘤性病变,因为没有细胞复制。与其他部位不同,前颅窝颅外海绵状血管瘤的切除似乎可以减少出血。