Yang Hung-Hsu, Miao Yong, Chen Yu-Tsung, Hu Zhi-Qi
Department of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou City, Guangdong Province, China.
Department of Dermatology, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan.
J Cosmet Dermatol. 2019 Apr;18(2):594-601. doi: 10.1111/jocd.12731. Epub 2018 Sep 10.
Minimally invasive techniques, including superficial liposuction with automatic shaver curettage (LC), subcutaneous laser treatment, and microwave-based therapy have been developed to treat osmidrosis. Few studies have compared these three techniques in relation to clinical efficacy, life quality improvement, and downtime.
We aim to evaluate clinical results and life quality improvement, in addition to downtime and complications, between these three techniques.
PATIENTS/METHODS: Clinical records of patients treated with these three minimally invasive techniques for axillary osmidrosis were retrospectively reviewed. Hyperhidrosis disease severity scale, Dermatology Life of Quality Index, clinical improvement, complication, and recurrence were assessed.
Among 403 patients, 168 received microwave-based therapy, 119 received subcutaneous laser treatment, and 116 received LC. All treatments showed significant improvements (P < 0.001) in HDSS, DLQI and clinical result after 3 and 12 months comparing to the baseline. But the improvements of subcutaneous laser were significantly inferior to microwave-base therapy and LC. Patients who received LC had a significantly longer downtime (P < 0.001) than those who received other treatments. The recurrence rate was significantly higher in the subcutaneous laser treatment group, and the microwave-based therapy group exhibited a longer recurrence duration (P < 0.001). LC group presented higher complication rate than other treatments.
Comparing to other treatments, microwave-based therapy was effective in treating osmidrosis with minimal downtime, recurrence, and complications. It could be a durable and effective therapeutic modality for osmidrosis and is less operator-dependent. It may be considered as a first-line treatment for axillary osmidrosis.
已开发出包括使用自动剃须刀刮吸法（LC）进行浅表吸脂、皮下激光治疗和微波疗法在内的微创技术来治疗腋臭。很少有研究比较这三种技术在临床疗效、生活质量改善和恢复时间方面的差异。
我们旨在评估这三种技术在临床效果、生活质量改善、恢复时间和并发症方面的差异。
患者/方法：回顾性分析接受这三种微创技术治疗腋臭患者的临床记录。评估多汗症疾病严重程度量表、皮肤病生活质量指数、临床改善情况、并发症和复发情况。
在403例患者中，168例接受微波疗法，119例接受皮下激光治疗，116例接受LC治疗。与基线相比，所有治疗在3个月和12个月时的多汗症疾病严重程度量表（HDSS）、皮肤病生活质量指数（DLQI）和临床结果均有显著改善（P < 0.001）。但皮下激光治疗的改善明显不如微波疗法和LC治疗。接受LC治疗的患者恢复时间明显长于接受其他治疗的患者（P < 0.001）。皮下激光治疗组的复发率明显更高，微波疗法组的复发持续时间更长（P < 0.001）。LC组的并发症发生率高于其他治疗组。
与其他治疗方法相比，微波疗法治疗腋臭有效，恢复时间短、复发率低且并发症少。它可能是一种持久有效的腋臭治疗方式，且对操作者的依赖性较小。它可被视为腋臭的一线治疗方法。
