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前瞻性随机对照双盲研究比较听诊法和肺部超声在评估涉及单肺通气的择期胸外科手术中双腔管位置的应用,该研究在一家三级癌症研究所进行。

A prospective randomized controlled double-blind study comparing auscultation and lung ultrasonography in the assessment of double lumen tube position in elective thoracic surgeries involving one lung ventilation at a tertiary care cancer institute.

机构信息

Department of Anesthesiology, Critical Care and Pain, Tata Memorial Hospital, Homi Bhabha National Institute, Mumbai, India.

出版信息

Korean J Anesthesiol. 2019 Feb;72(1):24-31. doi: 10.4097/kja.d.17.00081. Epub 2018 Sep 12.

Abstract

BACKGROUND

As lung ultrasound (LUS) can be used to identify regional lung ventilation and collapse, we hypothesize that LUS can be better than auscultation in assessing lung isolation and determining double lumen tube (DLT) position.

METHODS

A randomized controlled study was conducted in tertiary care cancer institute from November 2014 to December 2015, including 100 adult patients undergoing elective thoracic surgeries. Patients with tracheostomy, difficult airway and pleural-based pathologies were excluded. After anesthesia induction and DLT insertion, patients were randomized into group A (auscultation) and group B (LUS). Regional ventilation was assessed by experienced anesthesiologists using the respective method for each group. Final confirmation of DLT position with a bronchoscope was performed by a blinded anesthesiologist. Contingency tables were plotted to determine sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy for each method.

RESULTS

Data from 91 patients were analyzed (group A = 47, group B = 44). Compared with auscultation, LUS had significantly higher sensitivity (94.1% vs. 73.3%, P = 0.010), PPV (57.1% vs. 35.5%, P = 0.044), NPV (93.8% vs. 75.0%, P = 0.018), accuracy (70.5% vs. 48.9%, P = 0.036) and required longer median time (161.5 vs. 114 s, P < 0.001) for assessment of DLT position. Differences in specificity (55.6% vs. 37.5%, P = 0.101) and area under curve (0.748; 95% CI: 0.604-0.893 vs. 0.554, 95% CI: 0.379-0.730; P = 0.109) were not significant.

CONCLUSIONS

Compared to auscultation, LUS is a superior method for assessing lung isolation and determining DLT position.

摘要

背景

由于肺部超声(LUS)可用于识别区域性肺通气和萎陷,我们假设 LUS 在评估肺隔离和确定双腔管(DLT)位置方面可能优于听诊。

方法

这是一项 2014 年 11 月至 2015 年 12 月在三级肿瘤研究所进行的随机对照研究,纳入了 100 例接受择期胸部手术的成年患者。排除气管造口术、困难气道和胸膜相关病变的患者。麻醉诱导和 DLT 插入后,患者随机分为听诊组(A 组)和超声组(B 组)。两组分别由经验丰富的麻醉医师采用各自的方法评估区域通气。由一位盲法麻醉医师使用支气管镜对 DLT 位置进行最终确认。绘制列联表以确定每种方法的敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)和准确性。

结果

分析了 91 例患者的数据(A 组=47 例,B 组=44 例)。与听诊相比,LUS 的敏感性(94.1% vs. 73.3%,P=0.010)、PPV(57.1% vs. 35.5%,P=0.044)、NPV(93.8% vs. 75.0%,P=0.018)、准确性(70.5% vs. 48.9%,P=0.036)均显著更高,而评估 DLT 位置所需的中位数时间更长(161.5 秒 vs. 114 秒,P<0.001)。特异性(55.6% vs. 37.5%,P=0.101)和曲线下面积(0.748;95%CI:0.604-0.893 vs. 0.554,95%CI:0.379-0.730;P=0.109)无显著差异。

结论

与听诊相比,LUS 是评估肺隔离和确定 DLT 位置的更好方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/810f/6369345/4d74fb4a6382/kja-d-17-00081f1.jpg

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