Harnod Tomor, Lin Cheng-Li, Kao Chia-Hung
Department of Neurosurgery, Hualien Tzu Chi General Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, Taiwan.
College of Medicine, Tzu Chi University, Hualien 970, Taiwan.
J Clin Med. 2018 Sep 11;7(9):269. doi: 10.3390/jcm7090269.
To investigate the risk and risk factors for suicide attempt by patients with regular migraines (RM) and status migrainosus (SM) in Taiwan.
We analyzed a subset of the National Health Insurance Research Database of Taiwan and enrolled patients (≥20 years old) who had ever received a diagnosis of RM or SM between 2000 and 2012 in the RM and SM cohort. The SM cohort included 13,605 patients, the RM cohort had 21,485 patients, and the comparison cohort contained approximately four times that many patients. We calculated the adjusted hazard ratios and 95% confidence intervals (CI) for suicide attempts after adjusting for age, sex, monthly income, urbanization level, occupation, and comorbidities.
The SM cohort had a 1.81-fold risk of attempting suicide (95% CI = 1.14⁻2.89) compared to the comparison cohort. Other factors that predispose patients with SM to attempt suicide include the following: female sex, relatively young age (<50 years old), and low monthly income (<15,000 New Taiwan Dollars, approximately equivalent to 495 US Dollars). Additionally, the risk of attempting suicide only increased in patients who had been diagnosed with SM for longer than five years.
SM is associated with a higher risk for suicide attempt in migraineurs in Taiwan. This finding is important to clinicians and government officials seeking to prevent patients from attempting suicide in Taiwan and other similar East Asian countries.
调查台湾地区患有普通偏头痛（RM）和偏头痛持续状态（SM）的患者自杀未遂的风险及风险因素。
我们分析了台湾地区国民健康保险研究数据库的一个子集，纳入了2000年至2012年间在RM和SM队列中曾被诊断为RM或SM的患者（≥20岁）。SM队列包括13605名患者，RM队列有21485名患者，对照队列的患者数量约为前两者的四倍。在对年龄、性别、月收入、城市化水平、职业和合并症进行调整后，我们计算了自杀未遂的调整后风险比和95%置信区间（CI）。
与对照队列相比，SM队列自杀未遂风险为1.81倍（95%CI = 1.14⁻2.89）。使SM患者易发生自杀未遂的其他因素包括：女性、相对年轻（<50岁）和月收入低（<15000新台币，约合495美元）。此外，仅在被诊断为SM超过五年的患者中，自杀未遂风险才会增加。
在台湾地区，SM与偏头痛患者更高的自杀未遂风险相关。这一发现对于台湾地区以及其他类似东亚国家中试图预防患者自杀未遂的临床医生和政府官员而言具有重要意义。
