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儿童和青少年股骨头坏死与健康相关生活质量

NECROSIS OF THE FEMORAL HEAD AND HEALTH-RELATED QUALITY OF LIFE OF CHILDREN AND ADOLESCENTS.

作者信息

Matos Marcos Almeida, Silva Luanne Lisle Dos Santos, Alves Giordano Bruno, de Alcântara Walter Silva, Veiga Davi

机构信息

Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil.

Santa Casa de Misericórdia da Bahia, Salvador, BA, Brazil.

出版信息

Acta Ortop Bras. 2018;26(4):227-230. doi: 10.1590/1413-785220182604174253.

Abstract

OBJECTIVE

To verify the impact of avascular necrosis of the femoral head on the quality of life of children and adolescents with Perthes disease and sickle cell disease.

METHODS

A comparative study including 24 children between eight and 18 years old with avascular necrosis of the femoral head secondary to Perthes disease and sickle cell disease (Group with Necrosis) and 24 children considered asymptomatic (Group without Necrosis). Clinical and sociodemographic data were collected and the PedsQL 4.0 and the Charnley score for hip dysfunction were applied.

RESULTS

There was no difference in the overall score and in any domain when comparing the Perthes group (global = 73.1) and the sickle cell disease group (global = 65.9). When comparing the groups with necrosis and without necrosis, the Perthes group had a lower overall score only for the Physical Functioning domain (87.5 versus 68.5); sickle cell disease group had a lower overall score (64.9 versus 79.4) and in the Physical Functioning (68.5 versus 87.5) and School Functioning (62.9 versus 73.7) domains.

CONCLUSION

Avascular necrosis of the femoral head produces lower quality of life scores both in the global evaluation and in the domains Physical Functioning and School Functioning. Necrosis, bilateral lesion, and hip function were found to be associated with the loss of quality of life.

摘要

目的

验证股骨头缺血性坏死对患有佩特兹病和镰状细胞病的儿童及青少年生活质量的影响。

方法

一项对比研究,纳入24名8至18岁继发于佩特兹病和镰状细胞病的股骨头缺血性坏死儿童(坏死组)以及24名无症状儿童(无坏死组)。收集临床和社会人口学数据,并应用儿童生活质量量表4.0(PedsQL 4.0)和髋关节功能障碍查恩利评分。

结果

比较佩特兹病组(总体评分=73.1)和镰状细胞病组(总体评分=65.9)时,总体评分及任何领域均无差异。比较有坏死组和无坏死组时,佩特兹病组仅在身体功能领域总体评分较低(87.5对68.5);镰状细胞病组总体评分较低(64.9对79.4),且在身体功能(68.5对87.5)和学校功能(62.9对73.7)领域也较低。

结论

股骨头缺血性坏死在总体评估以及身体功能和学校功能领域均导致较低的生活质量评分。发现坏死、双侧病变和髋关节功能与生活质量下降相关。

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1
Hip Dysfunction and Quality of Life in Patients With Sickle Cell Disease.镰状细胞病患者的髋关节功能障碍与生活质量
Clin Pediatr (Phila). 2015 Dec;54(14):1354-8. doi: 10.1177/0009922815586051. Epub 2015 May 13.
3
Avascular necrosis of the femoral head in sickle cell disease patients.
Ortop Traumatol Rehabil. 2012 Mar-Apr;14(2):155-60. doi: 10.5604/15093492.992286.
5
Prognosis and prognostic factors of Legg-Calve-Perthes disease.Legg-Calve-Perthes病的预后及预后因素
J Pediatr Orthop. 2011 Sep;31(2 Suppl):S147-51. doi: 10.1097/BPO.0b013e318223b470.

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