Veznedaroglu Baybars, Dilbaz Nesrin, Uzun Ozcan, Isik Erdal
Psychiatry, Ege University, Izmir, Turkey.
Nesrin Dilbaz Psychiatry, NP Brain Hospital, Uskudar University, Ahmet Tevfik Ileri cad. No: 18, Umraniye, Istanbul 34768, Turkey.
Ther Adv Psychopharmacol. 2018 May 4;8(10):271-285. doi: 10.1177/2045125318772712. eCollection 2018 Oct.
In this review, we have attempted to share our 10 years' clinical experience with aripiprazole use and switching from other antipsychotics to aripiprazole. There are various reasons for switching, including a partial or complete lack of efficacy, adverse side effects, and partial or noncompliance with medication. Aripiprazole has some unique receptor-binding qualities that provides some advantages over other antipsychotics in certain clinical situations. We have covered potential clinical scenarios for aripiprazole use as a single agent and switching from other agents in inpatient and outpatient settings. Patients switched from other antipsychotics to aripiprazole have been shown to benefit from significant improvements in clinical response and tolerability. This review examines the strategies for switching patients from antipsychotic drugs to aripiprazole.
在本综述中，我们试图分享我们在使用阿立哌唑以及从其他抗精神病药物换用阿立哌唑方面的10年临床经验。换药的原因多种多样，包括部分或完全缺乏疗效、不良副作用以及部分或不依从用药。阿立哌唑具有一些独特的受体结合特性，在某些临床情况下比其他抗精神病药物具有一些优势。我们涵盖了阿立哌唑作为单一药物使用以及在住院和门诊环境中从其他药物换用阿立哌唑的潜在临床情况。已证明从其他抗精神病药物换用阿立哌唑的患者在临床反应和耐受性方面有显著改善并从中获益。本综述探讨了将患者从抗精神病药物换用阿立哌唑的策略。
