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胃窦残留的临床情况。

The clinical aspect of retained gastric antrum.

作者信息

Lee C H, P'eng F K, Lui W Y

出版信息

Arch Surg. 1986 Oct;121(10):1181-6. doi: 10.1001/archsurg.1986.01400100093018.

Abstract

Thirty symptomatic patients with retained gastric antrum proved pathologically and/or by isotopic visualization were studied and treated from 1968 to 1983. The latent periods from the antral exclusion to the occurrence of anastomotic ulcers after a subtotal gastrectomy with Billroth's type II reconstruction varied from a few days to 19 years, with an average of 2.8 years. Fasting serum gastrin levels were normal in 14 of 21 patients and were intermittently high in some patients. The basal to maximal acid-output ratio was greater than 0.6 in 69% of the patients; primary cimetidine treatment was effective in three of five patients. Thirty-five operations on 27 patients were divided into six groups; all of these 27 patients eventually underwent resection of retained gastric antrum. We concluded that resection remains the best treatment for anastomotic ulcer related to retained gastric antrum. Additional truncal vagotomy did not provide additional benefit to these patients. Furthermore, cimetidine can be useful to control the symptoms for preoperative preparation or definitive treatment in high-risk patients.

摘要

1968年至1983年期间,对30例经病理检查和/或同位素显像证实有胃窦残留的有症状患者进行了研究和治疗。在毕Ⅱ式胃大部切除术后,从胃窦旷置到吻合口溃疡发生的潜伏期从几天到19年不等,平均为2.8年。21例患者中14例空腹血清胃泌素水平正常,部分患者间歇性升高。69%的患者基础胃酸分泌量与最大胃酸分泌量之比大于0.6;五例患者中有三例接受西咪替丁初始治疗有效。对27例患者进行了35次手术,分为六组;所有这27例患者最终均接受了残留胃窦切除术。我们得出结论,手术切除仍然是治疗与残留胃窦相关的吻合口溃疡的最佳方法。附加迷走神经干切断术对这些患者并无额外益处。此外,西咪替丁可用于控制高危患者术前准备或确定性治疗的症状。

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