Griselli Massimo, Sinha Raina, Jang Subin, Perri Gianluigi, Adachi Iki
Division of Pediatric Cardiac Surgery, Department of Surgery, University of Minnesota Masonic Children's Hospital, Minneapolis, MN, United States.
Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy.
Front Cardiovasc Med. 2018 Aug 28;5:115. doi: 10.3389/fcvm.2018.00115. eCollection 2018.
Mechanical circulatory support (MCS) for failing single ventricle (SV) physiology is a complex and challenging problem, which has not yet been satisfactorily addressed. Advancements in surgical strategies and techniques along with intensive care management have substantially improved the outcomes of neonatal palliation for SV physiology, particularly for hypoplastic left heart syndrome (HLHS). This is associated with a steady increase in the number of SV patients who are susceptible to develop heart failure (HF) and would potentially require MCS at a certain stage in their palliation. We have reviewed the literature regarding the reported modalities of MCS use in the management of SV patients. This includes analysis of various devices and strategies used for failing circulation at distinct stages of the SV pathway: after neonatal palliation, after the superior cavo-pulmonary connection (SCPC), and after total cavo-pulmonary connection (TCPC).
针对功能衰竭的单心室（SV）生理状况的机械循环支持（MCS）是一个复杂且具有挑战性的问题，尚未得到令人满意的解决。手术策略和技术的进步以及重症监护管理已显著改善了SV生理状况新生儿姑息治疗的结果，尤其是对于左心发育不全综合征（HLHS）。这与易发生心力衰竭（HF）且在姑息治疗的某个阶段可能需要MCS的SV患者数量稳步增加有关。我们回顾了有关在SV患者管理中使用MCS的报道方式的文献。这包括分析在SV路径不同阶段用于循环衰竭的各种设备和策略：新生儿姑息治疗后、上腔静脉-肺动脉连接（SCPC）后以及全腔静脉-肺动脉连接（TCPC）后。
