Weingarten H, Feder J
Biochem Biophys Res Commun. 1986 Sep 30;139(3):1184-7. doi: 10.1016/s0006-291x(86)80302-3.
A series of synthetic peptide substrates for vertebrate collagenase having the structure Ac-Pro-Leu-Gly-X-Leu-Gly-OC2H5, where X is Leu, Ile, Val, Phe and Ala, have been prepared. Collagenolytic enzymes from various sources cleave these substrates with differing relative rate patterns. This series of peptides should be valuable for characterization of collagenases.
已制备出一系列具有结构Ac-Pro-Leu-Gly-X-Leu-Gly-OC2H5的脊椎动物胶原酶合成肽底物，其中X为亮氨酸、异亮氨酸、缬氨酸、苯丙氨酸和丙氨酸。来自不同来源的胶原分解酶以不同的相对速率模式切割这些底物。这一系列肽对于胶原酶的表征应该是有价值的。
