肌母细胞在人体梗死心脏中的长期植入（16 年）。
Long-Term Engraftment (16 Years) of Myoblasts in a Human Infarcted Heart.
机构信息
Department of Pathology, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
University Paris Descartes, Sorbonne Paris Cité, Paris, France.
出版信息
Stem Cells Transl Med. 2018 Oct;7(10):705-708. doi: 10.1002/sctm.18-0017. Epub 2018 Sep 13.
We report the case of a patient who had undergone injections of myoblasts in an infarct area 16 years before being referred for heart transplantation. The pathological examination of the explanted heart found persisting myotubes embedded in fibrosis. This finding supports the ability of myoblasts to survive in harsh environments, which can make them appealing candidates for transplantation in diseases requiring supply of new myogenic cells. Stem Cells Translational Medicine 2018;7:705-708.
我们报告了一例患者，该患者在 16 年前因心脏移植而被转诊，此前曾在梗死区域接受肌母细胞注射。对移植心脏的病理学检查发现，持续存在的肌管嵌入纤维化中。这一发现支持肌母细胞在恶劣环境中生存的能力，这使它们成为需要供应新的肌原细胞的疾病中移植的有吸引力的候选物。Stem Cells Translational Medicine 2018;7:705-708。
Zotero 插件