Novoa-Parra C D, Pérez-Ortiz S, López-Trabucco R E, Blas-Dobón J A, Rodrigo-Pérez J L, Lizaur-Utrilla A
Servicio de Cirugía Ortopédica y Traumatología, Hospital Universitario Dr. Peset, Valencia, España.
Servicio de Cirugía Ortopédica y Traumatología, Hospital Universitario Dr. Peset, Valencia, España.
Rev Esp Cir Ortop Traumatol (Engl Ed). 2019 May-Jun;63(3):233-238. doi: 10.1016/j.recot.2018.06.002. Epub 2018 Sep 10.
To identify the factors with influence on the development of avascular necrosis of the femoral head (ANFH) in patients with non-displaced femoral neck fractures treated with internal fixation.
Retrospective study of cases and controls. We included non-displaced femoral neck fractures treated with internal fixation, and that presented ANFH with a postoperative follow-up of at least 2 years. The baseline variables, active comorbidities of the patients, the time for surgery and the number of screws used for osteosynthesis were recorded. Comparisons were made between the groups, those that presented ANFH and those that did not. By area under the curve, the cut-offs of age and time for surgery were located.
An association between sex, active comorbidities and number of screws used and the development of ANFH was not observed. The cut-off points for age and time for surgery were≤69 years and≤43hours, respectively. No significant correlation was observed for the cut-off time for surgery. In the multivariate analysis, age≤69 years was a significant predictor of the development of ANFH (OR 4.6; 95% CI 1.1 to 17.9; P=.028).
The patients aged 69 years or younger were at increased risk of developing ANFH after undisplaced femoral neck fracture treated with percutaneous screws.
确定影响采用内固定治疗的无移位股骨颈骨折患者发生股骨头缺血性坏死(ANFH)的因素。
病例对照回顾性研究。纳入采用内固定治疗的无移位股骨颈骨折患者,且术后随访至少2年出现ANFH的患者。记录患者的基线变量、现存合并症、手术时间及用于骨合成的螺钉数量。对出现ANFH的组和未出现ANFH的组进行比较。通过曲线下面积确定年龄和手术时间的临界值。
未观察到性别、现存合并症及所用螺钉数量与ANFH发生之间存在关联。年龄和手术时间的临界值分别为≤69岁和≤43小时。手术临界时间未观察到显著相关性。在多变量分析中,年龄≤69岁是ANFH发生的显著预测因素(比值比4.6;95%置信区间1.1至17.9;P = 0.028)。
69岁及以下患者在采用经皮螺钉治疗无移位股骨颈骨折后发生ANFH的风险增加。