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Design and synthesis of N-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L -alanyl]-N-(indan-2-yl)glycine (CV-3317), a new, potent angiotensin converting enzyme inhibitor.

作者信息

Miyake A, Itoh K, Oka Y

出版信息

Chem Pharm Bull (Tokyo). 1986 Jul;34(7):2852-8. doi: 10.1248/cpb.34.2852.

DOI:10.1248/cpb.34.2852
PMID:3021350
Abstract
摘要

相似文献

1
Design and synthesis of N-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L -alanyl]-N-(indan-2-yl)glycine (CV-3317), a new, potent angiotensin converting enzyme inhibitor.新型强效血管紧张素转换酶抑制剂N-[N-[(S)-1-乙氧羰基-3-苯基丙基]-L-丙氨酰]-N-(茚满-2-基)甘氨酸（CV-3317）的设计与合成
Chem Pharm Bull (Tokyo). 1986 Jul;34(7):2852-8. doi: 10.1248/cpb.34.2852.
2
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3
Inhibition of angiotensin converting enzyme by CV-3317, a non-sulfhydryl compound.
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4
Antihypertensive action of a non-sulfhydryl angiotensin converting enzyme inhibitor (CV-3317) in various hypertensive models.
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[Synthesis and antiplatelet aggregating activity of several thiopyranylidene ketones and benzylidene indanones].
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Synthesis of a highly active angiotensin converting enzyme inhibitor: 2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S)-2- azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe 498).
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Synthesis and pharmacological activities of some 2,3-substituted bicyclo[3.3.0]oct-7-en-1-one and 2,3-substituted 4,5,6,7-tetrahydro (or perhydro) indan-1-one derivatives.某些2,3-取代的双环[3.3.0]辛-7-烯-1-酮及2,3-取代的4,5,6,7-四氢（或全氢）茚-1-酮衍生物的合成与药理活性
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1-Indancarboxylic acids. I. Electrophilic substitution reactions of 1-indancarboxylic acid and synthesis of 6-substituted 1-indancarboxylic acids as potential antinflammatory agents.
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