Khalloufi A, Ouarssani A, Er-Rami M, Fellah H, Sebti F, Moudden M K
Laboratoire d'hématologie, hôpital militaire Moulay Ismail de Meknès, Bd El Hanssali, 50000 Meknès, Maroc.
Service de pneumologie, hôpital militaire Moulay Ismail de Meknès, Bd El Hanssali, 50000 Meknès, Maroc.
Rev Mal Respir. 2018 Nov;35(9):956-958. doi: 10.1016/j.rmr.2017.09.012. Epub 2018 Sep 10.
Chronic obstructive pulmonary disease (COPD) is a common respiratory disorder. Its exacerbation is infectious in more than half of the cases: with viral priority, while parasitic causes remain exceptional. In this work, we report a case of a COPD exacerbation caused by a visceral leishmaniasis (VL) complicated by a macrophage activation syndrome in an adult living in a Moroccan non-endemic region for this of leismaniasis form. In such atypical clinical feature, the diagnosis of VL was based on the myelogram after presence of peripheral cytopenia. Despite the seriousness of these pathologies, the early and specific treatment of VL allows a quickly improvement in the disorders caused by these diseases.
慢性阻塞性肺疾病（COPD）是一种常见的呼吸系统疾病。其急性加重在半数以上病例中由感染引起：以病毒感染为主，而寄生虫感染病因仍较为罕见。在本研究中，我们报告了一例居住在摩洛哥利什曼病非流行地区的成年人，因内脏利什曼病（VL）并发巨噬细胞活化综合征导致COPD急性加重的病例。在这种非典型临床特征中，VL的诊断基于外周血细胞减少出现后的骨髓检查结果。尽管这些疾病较为严重，但VL的早期特异性治疗可使这些疾病所致的紊乱迅速改善。
