注意力缺陷多动障碍成年人的健康相关生活质量和工作效率：一项基于英国网络的横断面调查。
Health-Related Quality of Life and Work Productivity of Adults With ADHD: A U.K. Web-Based Cross-Sectional Survey.
作者信息
Joseph Alain, Kosmas Charlotte E, Patel Chloe, Doll Helen, Asherson Philip
机构信息
1 Shire, Zug, Switzerland.
2 ICON, Oxfordshire, UK.
出版信息
J Atten Disord. 2018 Sep 14;23(13):1610-1623. doi: 10.1177/1087054718799367. Print 2019 Nov 1.
OBJECTIVE
The objective of this study was to assess health-related quality of life (HRQoL) in adult ADHD.
METHOD
U.K. residents aged 18 to 55 years with ADHD and no major mental health comorbidities completed an online survey of disorder history, the EuroQoL 5-Dimensions 5-Level (EQ-5D-5L), and the Work Productivity and Activity Impairment Questionnaire: General Health (WPAI:GH). ADHD Rating Scale-IV (ADHD-RS-IV) score was assessed by telephone.
RESULTS
In total, 233 participants completed the study (mean age 32.6 years; 65.2% women). Mean ( SD) ADHD-RS-IV total score, EQ-5D utility, and visual analog scale (VAS) scores were 43.5 (7.88), 0.74 (.21), and 69.8 (17.76), respectively. Mean ( SD) WPAI:GH scores indicated that health problems caused 45.7% (29.9) overall work impairment and 45.8% (28.9) impairment in regular daily activities. Greater work and activity impairment were both significantly independently associated with lower utility after adjusting for age, gender, and somatic comorbidities.
CONCLUSION
Adult ADHD impairs HRQoL, work productivity, and regular daily activities.
目的
本研究的目的是评估成人注意力缺陷多动障碍（ADHD）患者的健康相关生活质量（HRQoL）。
方法
年龄在18至55岁之间、患有ADHD且无重大心理健康合并症的英国居民完成了一项关于疾病史、欧洲五维健康量表5级（EQ-5D-5L）和工作效率与活动障碍问卷：总体健康（WPAI：GH）的在线调查。通过电话评估ADHD评定量表第四版（ADHD-RS-IV）得分。
结果
共有233名参与者完成了研究（平均年龄32.6岁；65.2%为女性）。ADHD-RS-IV总分、EQ-5D效用值和视觉模拟量表（VAS）得分的均值（标准差）分别为43.5（7.88）、0.74（0.21）和69.8（17.76）。WPAI：GH得分的均值（标准差）表明，健康问题导致总体工作效率下降45.7%（29.9），日常常规活动能力下降45.8%（28.9）。在对年龄、性别和躯体合并症进行校正后，工作效率和活动能力的更大下降均与较低的效用值显著独立相关。
结论
成人ADHD会损害健康相关生活质量、工作效率和日常常规活动能力。
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