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2
[The Kono-S anastomosis in surgery for Crohn's disease : First results of a new functional end-to-end anastomotic technique after intestinal resection in patients with Crohn's disease in Germany].[克罗恩病手术中的科诺-斯吻合术:德国克罗恩病患者肠道切除术后一种新型功能性端端吻合技术的初步结果]
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本文引用的文献

1
Surgical management of Crohn's disease.克罗恩病的外科治疗。
Langenbecks Arch Surg. 2013 Jan;398(1):13-27. doi: 10.1007/s00423-012-0919-7. Epub 2012 Feb 21.
2
Determinants for postoperative complications after laparoscopic intestinal resection for Crohn's disease.腹腔镜肠切除术治疗克罗恩病术后并发症的决定因素。
Surg Endosc. 2012 Apr;26(4):933-8. doi: 10.1007/s00464-011-1970-0. Epub 2011 Oct 15.
3
Surgery for intestinal Crohn's disease recurrence.肠克罗恩病复发的手术治疗。
Surgery. 2010 Nov;148(5):936-46. doi: 10.1016/j.surg.2010.02.001. Epub 2010 Apr 2.
4
Clinical characteristics of inflammatory bowel disease in Turkey: a multicenter epidemiologic survey.土耳其炎症性肠病的临床特征:一项多中心的流行病学调查。
J Clin Gastroenterol. 2009 Jan;43(1):51-7. doi: 10.1097/MCG.0b013e3181574636.
5
A meta-analysis comparing incidence of recurrence and indication for reoperation after surgery for perforating versus nonperforating Crohn's disease.一项比较穿孔性与非穿孔性克罗恩病手术后复发率及再次手术指征的荟萃分析。
Am J Gastroenterol. 2008 Jan;103(1):196-205. doi: 10.1111/j.1572-0241.2007.01548.x. Epub 2007 Sep 25.
6
A comparison of segmental vs subtotal/total colectomy for colonic Crohn's disease: a meta-analysis.结肠克罗恩病节段性结肠切除术与次全/全结肠切除术的比较:一项荟萃分析
Colorectal Dis. 2006 Feb;8(2):82-90. doi: 10.1111/j.1463-1318.2005.00903.x.
7
Could immunosuppressive drugs reduce recurrence rate after second resection for Crohn disease?免疫抑制药物能否降低克罗恩病二次切除术后的复发率?
Inflamm Bowel Dis. 2004 Sep;10(5):491-5. doi: 10.1097/00054725-200409000-00001.
8
Postoperative maintenance of Crohn's disease remission with 6-mercaptopurine, mesalamine, or placebo: a 2-year trial.使用6-巯基嘌呤、美沙拉嗪或安慰剂进行克罗恩病缓解期的术后维持治疗:一项为期2年的试验。
Gastroenterology. 2004 Sep;127(3):723-9. doi: 10.1053/j.gastro.2004.06.002.
9
Risk factors for surgery and recurrence in 907 patients with primary ileocaecal Crohn's disease.907例原发性回盲部克罗恩病患者手术及复发的危险因素
Br J Surg. 2000 Dec;87(12):1697-701. doi: 10.1046/j.1365-2168.2000.01589.x.
10
Risk factors for surgery and postoperative recurrence in Crohn's disease.克罗恩病手术及术后复发的危险因素
Ann Surg. 2000 Jan;231(1):38-45. doi: 10.1097/00000658-200001000-00006.

肠道克罗恩病的手术治疗:多学科方法的结果

Surgery for Intestinal Crohn's Disease: Results of a multidisciplinary approach.

作者信息

Atasoy Deniz, Aghayeva Afag, Aytaç Erman, Erenler İlknur, Çelik Aykut Ferhat, Baca Bilgi, Karahasanoğlu Tayfun, Hamzaoğlu İsmail

机构信息

Department of General Surgery, Acıbadem University School of Medicine, İstanbul, Turkey.

Department of Gastroenterology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.

出版信息

Turk J Surg. 2018 Aug 31;34(3):225-228. doi: 10.5152/turkjsurg.2017.3885.

DOI:10.5152/turkjsurg.2017.3885
PMID:30216166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6173600/
Abstract

OBJECTIVES

Crohn's disease is a chronic inflammatory bowel disease that requires lifelong multidisciplinary management. Seventy percent of patients affected by Crohn's disease will require at least one surgical procedure over their lifetime. The aim of this retrospective study was to present our series of patients suffering from Crohn's disease who were scheduled for surgery by a multidisciplinary team.

MATERIAL AND METHODS

The data were retrieved from a review of 950 patients with Crohn's disease treated at our institution between March 2000 and March 2016. Only patients with intestinal Crohn's disease were included into the study. A multidisciplinary team assessed the decision to perform surgery.

RESULTS

There were 203 patients who underwent surgery included in this study. One hundred and sixty-six were intestinal and 37 were perianal Crohn's disease. The mean age was 36±11.5 (range, 12-75) years. Ninety-two were stricturing, 45 were fistulizing, and 12 were inflammatory. The most commonly affected site was the ileocecal region (n=109, 65.7%), and the most common surgical procedure was the ileocecal resection (n=109, 65.6%). Laparoscopic approach was the procedure of choice in 56 (33.7%) patients. Of the patients enrolled, the most common early (<30 days) complications observed were the wound infection as the first (n=11) and anastomotic leak as the second (n=10). The mortality rate was 2.4% (n=4).

CONCLUSION

Multidisciplinary approach to Crohn's disease may decrease the surgical complications and recurrence rates leading to a better treatment.

摘要

目的

克罗恩病是一种慢性炎症性肠病,需要终身多学科管理。70%的克罗恩病患者一生中至少需要进行一次外科手术。这项回顾性研究的目的是介绍我们多学科团队安排进行手术的一系列克罗恩病患者。

材料与方法

数据来自对2000年3月至2016年3月在我院接受治疗的950例克罗恩病患者的回顾。仅纳入肠道克罗恩病患者进行研究。多学科团队评估手术决策。

结果

本研究纳入203例接受手术的患者。166例为肠道克罗恩病,37例为肛周克罗恩病。平均年龄为36±11.5岁(范围12 - 75岁)。92例为狭窄型,45例为瘘管型,12例为炎症型。最常受累部位是回盲部(n = 109,65.7%),最常见的外科手术是回盲部切除术(n = 109,65.6%)。56例(33.7%)患者选择腹腔镜手术。在纳入的患者中,观察到最常见的早期(<30天)并发症,首先是伤口感染(n = 11),其次是吻合口漏(n = 10)。死亡率为2.4%(n = 4)。

结论

克罗恩病的多学科治疗方法可能会降低手术并发症和复发率,从而带来更好的治疗效果。