不同解剖部位淋病奈瑟菌多重感染病例中回旋酶 A 基因型不一致的频率。
The Frequency of Discordant Gyrase A Genotypes Among Cases of Multiple Neisseria gonorrhoeae Infections at Different Anatomic Sites.
机构信息
From the David Geffen School of Medicine.
Los Angeles Lesbian Gay Bisexual and Transgender Center, Los Angels, CA.
出版信息
Sex Transm Dis. 2019 Jan;46(1):e3-e4. doi: 10.1097/OLQ.0000000000000912.
Abstract
Gyrase A genotyping reliably predicts Neisseria gonorrhoeae susceptibility to ciprofloxacin. It is unknown whether concurrent infections at different anatomic sites harbor different susceptibility profiles. We found a 3.2% frequency of discordant gyrase A genotypes among concurrent but anatomically separate N. gonorrhoeae infections diagnosed at 2 laboratories in Los Angeles.
摘要
Gyrase A 基因分型能可靠地预测淋病奈瑟菌对环丙沙星的敏感性。目前尚不清楚不同解剖部位的同时感染是否具有不同的敏感性特征。我们在洛杉矶的 2 家实验室诊断出的同时发生但解剖部位不同的淋病奈瑟菌感染中，发现了 3.2%的 gyrase A 基因型不一致的情况。
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