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结膜骨化性迷离瘤的临床病理研究

[Clinicopathological study on conjunctival osseous choristoma].

作者信息

Zhao Y, Li H Q, Zhao H, Lin J Y

机构信息

Tianjin Eye Hospital and Institute, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Key Laboratory of Ophthalmology and Vision Science, Tianjin 300020, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2018 Sep 11;54(9):661-664. doi: 10.3760/cma.j.issn.0412-4081.2018.09.005.

DOI:10.3760/cma.j.issn.0412-4081.2018.09.005
PMID:30220180
Abstract

To summarize the clinical pathologic characteristics of conjunctival osseous choristoma. Retrospective case series study. Six cases of conjunctival osseous choristoma between January 2009 and June 2016 from Tianjin Eye Hosptial were reviewed retrospectively. The clinical features, CT characteristics and histological characteristics were analyzed. The 6 cases includes 3 male patients and 3 females. The age of the patients ranged from 4 to 20 years. Three cases involved with the right eye and the other 3 involved with the left eye. Major clinical feature of the patient is the flat uplift tumor in the superior temporal quadrant of the conjunctiva. CT features of conjunctival osseous choristoma revealed a oval calcium spot of eyeball surface. All the patients received surgery. Pathological examination showed that the tumor is composed of bone tissue which was surrounded by fibrous tissue, and Haversian canals are present in compact bone tissue. Five patients were followed for 23 months to 8 years. None of the patients relapsed after operation. The major feature of conjuncital osseous choristoma is a tumor in the superior temporal quadrant of conjunctiva. Imaging examination reveals a oval calcium spot of eyeball surface. Pathological examination reveals that the osseous tumor is composed of compact bone tissue which was surrounded by fibrous tissue.Haversian canals are present in compact bone tissue.Diagnosis is dependent on histopathological examination. It is not prone to relapse after complete resection surgery. .

摘要

总结结膜骨化性迷离瘤的临床病理特征。回顾性病例系列研究。回顾性分析2009年1月至2016年6月天津眼科医院收治的6例结膜骨化性迷离瘤患者的临床特征、CT表现及组织学特征。6例患者中男性3例,女性3例。年龄4~20岁。右眼3例,左眼3例。主要临床特征为结膜颞上象限扁平隆起肿物。结膜骨化性迷离瘤的CT表现为眼球表面椭圆形钙化斑。所有患者均接受手术治疗。病理检查显示肿瘤由纤维组织包绕的骨组织构成,致密骨组织中有哈弗斯管。5例患者随访23个月至8年,术后均无复发。结膜骨化性迷离瘤的主要特征为结膜颞上象限肿物。影像学检查显示眼球表面椭圆形钙化斑。病理检查显示骨肿瘤由纤维组织包绕的致密骨组织构成,致密骨组织中有哈弗斯管。诊断依靠组织病理学检查。完整切除术后不易复发。

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