Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX, U.S.A.
Clin Sci (Lond). 2018 Sep 16;132(17):1999-2001. doi: 10.1042/CS20180292. Print 2018 Sep 14.
The roles of the kidney are well defined, if there is a progressive loss in renal function, the kidney is no longer able to perform the listed tasks and chronic kidney disease (CKD) persists. In both clinical and experimental studies, NaHCO supplementation has been shown to improve glomerular filtration rate (GFR) as well as halt the progression toward end-stage renal disease (ESRD). In an article recently published in (vol (11) 1179-1197), Ray et al. presented an intriguing and timely study, which investigates the mechanisms involved in the protection that follows oral NaHCO ingestion. Here we comment on their research findings.
肾脏的功能明确，如果肾功能逐渐丧失，肾脏将无法执行上述任务，慢性肾脏病 (CKD) 将持续存在。在临床和实验研究中，补充碳酸氢钠已被证明可改善肾小球滤过率 (GFR)，并阻止向终末期肾病 (ESRD) 进展。在最近发表在 (卷 (11) 1179-1197) 的一篇文章中，Ray 等人提出了一项有趣且及时的研究，该研究调查了口服碳酸氢钠摄入后所产生保护作用的相关机制。在此，我们对他们的研究结果进行评论。
