Nkwabong Elie, Laure Bessi Badjan Ingrid, Sando Zacharie
1 Associate Professor, Department of Obstetrics & Gynecology, University Teaching Hospital / Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.
2 Student, Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.
Trop Doct. 2019 Jan;49(1):34-39. doi: 10.1177/0049475518798532. Epub 2018 Sep 15.
This cross-sectional descriptive study, aimed at accessing the accuracy of Pap smear in diagnosing cervical precancerous lesions, was carried out between 3 January and 30 April 2017. All women screened for cervical dysplasia by means of Pap smear with biopsy done for confirmation were subsequently recruited. Data were analysed using SPSS 20.0. A total of 231 women were screened for cervical dysplasia using Pap smear with 75 biopsies performed. Cervical dysplasia was noticed in 54 cases. The sensitivity, specificity, positive predictive and negative predictive values of Pap smear were 55.5%, 75%, 88.2% and 33.3%, respectively. The sensitivity of Pap smear remains low. Therefore, biopsy should be done in cases of macroscopic cervical architectural changes irrespective of the result of the Pap smear. Moreover, to reduce the number of women with cervical precancerous lesions, the government should make available financial resources to set up HPV vaccination programmes rather than screening programmes.
这项横断面描述性研究旨在评估巴氏涂片在诊断宫颈癌前病变方面的准确性,于2017年1月3日至4月30日进行。所有通过巴氏涂片筛查宫颈发育异常并进行活检以确诊的女性随后被纳入研究。使用SPSS 20.0对数据进行分析。共有231名女性通过巴氏涂片筛查宫颈发育异常,其中75例进行了活检。发现54例宫颈发育异常。巴氏涂片的敏感性、特异性、阳性预测值和阴性预测值分别为55.5%、75%、88.2%和33.3%。巴氏涂片的敏感性仍然较低。因此,无论巴氏涂片结果如何,在宫颈出现宏观结构变化的情况下都应进行活检。此外,为了减少患有宫颈癌前病变的女性数量,政府应提供财政资源来设立人乳头瘤病毒(HPV)疫苗接种项目,而不是筛查项目。