Li Loong T C, Coyle P V, Anderson M J, Allen G E, Connolly J H
Postgrad Med J. 1986 Jun;62(728):493-4. doi: 10.1136/pgmj.62.728.493.
A 48 year old man had a severe symmetrical arthritis of knee and ankle joints accompanied by an extensive purpuric rash of both legs and several areas of skin necrosis. No other system was clinically involved. Human serum parvovirus-specific IgM was present in a blood sample taken 2 weeks after the onset of the clinical illness indicating recent infection with this virus. The patient was treated with complete bed rest, and the application of saline soaks to both legs. He had a recurrence of the rash 5 weeks after onset, but otherwise made a complete recovery. Purpura with skin necrosis has not previously been reported in association with this virus.
一名48岁男性出现严重的膝关节和踝关节对称性关节炎,同时双下肢有广泛的紫癜疹和多处皮肤坏死。临床上未累及其他系统。在临床疾病发作2周后采集的血样中检测到人类血清细小病毒特异性IgM,表明近期感染了该病毒。患者接受了完全卧床休息治疗,并对双下肢进行盐水湿敷。发病5周后皮疹复发,但除此之外患者完全康复。此前尚无关于这种病毒与伴有皮肤坏死的紫癜相关的报道。