Lampen Shaun I R, Khurana Rahul N, Noronha Glenn, Brown David M, Wykoff Charles C
Ophthalmic Surg Lasers Imaging Retina. 2018 Sep 1;49(9):692-697. doi: 10.3928/23258160-20180831-07.
To study anatomic changes in the suprachoroidal space (SCS) following suprachoroidal injection of CLS-TA, triamcinolone acetonide injectable suspension.
Eyes with diabetic macular edema receiving CLS-TA were imaged serially using anterior segment spectral-domain optical coherence tomography to examine the SCS.
At the final imaging session, the SCS was not significantly different in study eyes (n = 14; 8.4 μm) compared to fellow eyes (n = 10; 8.1 μm; P = .698). Two eyes were imaged immediately before and 30 minutes after suprachoroidal injections; in these eyes, mean suprachoroidal width increased significantly following CLS-TA injection, 9.9 μm to 75.1 μm (P < .001), and subsequently returned to 14.9 μm 1 month after the final injection (P = .221).
Suprachoroidal CLS-TA injection caused a measurable increase in the SCS, which returned to preinjection levels by 1 month following injection with no apparent lasting impact on SCS anatomy. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:692-697.].
研究脉络膜上腔（SCS）在脉络膜上腔注射CLS-TA（曲安奈德注射用混悬液）后的解剖学变化。
使用眼前节光谱域光学相干断层扫描对接受CLS-TA治疗的糖尿病性黄斑水肿患者的眼睛进行连续成像，以检查脉络膜上腔。
在最后一次成像时，研究眼（n = 14；8.4μm）的脉络膜上腔与对侧眼（n = 10；8.1μm；P = 0.698）相比无显著差异。对2只眼睛在脉络膜上腔注射前及注射后30分钟进行成像；在这些眼中，CLS-TA注射后脉络膜上腔平均宽度显著增加，从9.9μm增至75.1μm（P < 0.001），并在最后一次注射后1个月时恢复至14.9μm（P = 0.221）。
脉络膜上腔注射CLS-TA可使脉络膜上腔出现可测量的增宽，注射后1个月时恢复至注射前水平，对脉络膜上腔解剖结构无明显持久影响。[《眼科手术、激光与视网膜成像》。2018；49：692 - 697。]
