Fan Wen, Zheng Xinhua, Yuan Songtao, Xie Ping, Liu Qinghuai
Ophthalmic Surg Lasers Imaging Retina. 2018 Sep 1;49(9):721-725. doi: 10.3928/23258160-20180831-12.
A 36-year-old man was diagnosed with Schwartz-Matsuo syndrome and received a scleral buckle surgery. Photoreceptor outer segments in aqueous humor were examined under electron microscope to confirm the diagnosis. Afterwards, 17 human angiogenesis and growth factor biomarkers were chosen to make simultaneous quantification in aqueous humor, among which the authors demonstrated the remarkable high expression of angiopoietin-2 in aqueous humor. This is the first reported case of angiogenesis / growth factor biomarkers in aqueous humor of the Schwartz-Matsuo Syndrome patient. Angiopoietin-2 level significantly increased in this patient's aqueous humor, which helped the authors to illuminate the pathogenic mechanisms underlying Schwartz-Matsuo syndrome. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:721-725.].
一名36岁男性被诊断为施瓦茨-松尾综合征，并接受了巩膜扣带手术。在电子显微镜下检查房水中的光感受器外节以确诊。之后，选择17种人类血管生成和生长因子生物标志物同时对房水进行定量分析，作者发现其中血管生成素-2在房水中显著高表达。这是首次报道施瓦茨-松尾综合征患者房水中血管生成/生长因子生物标志物的病例。该患者房水中血管生成素-2水平显著升高，这有助于作者阐明施瓦茨-松尾综合征的发病机制。[《眼科手术、激光与视网膜成像》。2018年；49:721 - 725。]
