Tansi Felista L, Rüger Ronny, Kollmeier Ansgar M, Rabenhold Markus, Steiniger Frank, Kontermann Roland E, Teichgraeber Ulf K, Fahr Alfred, Hilger Ingrid
Institute of Diagnostic and Interventional Radiology, Experimental Radiology, Jena University Hospital, Am klinikum 1, 07747 Jena, Germany.
Department of Pharmaceutical Technology, Friedrich-Schiller-University Jena, Lessingstrasse 8, 07743 Jena, Germany.
Data Brief. 2018 Aug 31;20:1048-1052. doi: 10.1016/j.dib.2018.08.110. eCollection 2018 Oct.
The underlying data demonstrates that the expression of endoglin in murine melanoma cells influences melanin production in the cells. Also, the data shows that melanin production is further increased when the cells are subcutaneously implanted in mice models and that the high melanin production prevents detection of the cells by fluorescence imaging. The processed data presented herein is related to a research article by Tansi et al. (2018) entitled "Endoglin based near-infrared fluorescence imaging of tumor models in mice using activatable liposomes".
基础数据表明，小鼠黑色素瘤细胞中内皮糖蛋白的表达会影响细胞中的黑色素生成。此外，数据显示，当将这些细胞皮下植入小鼠模型时，黑色素生成会进一步增加，并且高黑色素生成会妨碍通过荧光成像检测这些细胞。本文所呈现的处理后的数据与Tansi等人（2018年）发表的一篇题为《使用可激活脂质体对小鼠肿瘤模型进行基于内皮糖蛋白的近红外荧光成像》的研究文章相关。
