Liu Xiaole, Kong Dehui, Liu Yanbo, Fu Jia, Gao Peng, Chen Taibo, Fang Quan, Cheng Kang'an, Fan Zhongjie
Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Pacing Clin Electrophysiol. 2018 Nov;41(11):1441-1446. doi: 10.1111/pace.13500. Epub 2018 Oct 4.
Atrial fibrillation (AF) is an important arrhythmia associated with cardiovascular morbidity and mortality. This study is focused on exploring the potential relationship between short-term air pollution exposure and occurrence of AF.
A case-crossover design was used to investigate the effect of pollutants on AF occurrence among 100 patients from 2013 to 2014. The air pollutants included ambient particulate matter less than 2.5 μm in aerodynamic diameter (PM ), particulate matter less than 10 μm in aerodynamic diameter (PM ), nitrogen dioxide (NO ), sulfur dioxide (SO ), carbon monoxide (CO), and ozone (O ). Participants with cardiac implantable electronic devices implanted were followed-up to December 31, 2014.
A 10 μg/m increase of PM and PM was associated with 3.8% (95% confidence interval [CI]: 1.4-6.2) and 2.7% (95% CI: 0.6-4.8) increase in the risk of AF occurrence, respectively. No statistically significant association was noted with SO , NO , CO, and O .
Short-term exposure to particular matter, both PM and PM , is associated with an increased risk of AF. This further demonstrates the urgency for air quality monitoring and control in geographical area with intense pollution.
心房颤动（AF）是一种与心血管疾病发病率和死亡率相关的重要心律失常。本研究旨在探讨短期空气污染暴露与AF发生之间的潜在关系。
采用病例交叉设计，调查2013年至2014年期间100例患者中污染物对AF发生的影响。空气污染物包括空气动力学直径小于2.5μm的细颗粒物（PM ）、空气动力学直径小于10μm的可吸入颗粒物（PM ）、二氧化氮（NO ）、二氧化硫（SO ）、一氧化碳（CO）和臭氧（O ）。对植入心脏植入式电子设备的参与者随访至2014年12月31日。
PM 和PM 每增加10μg/m ，AF发生风险分别增加3.8%（95%置信区间[CI]：1.4 - 6.2）和2.7%（95%CI：0.6 - 4.8）。未发现与SO 、NO 、CO和O 存在统计学显著关联。
短期暴露于细颗粒物（PM 和PM ）与AF风险增加有关。这进一步证明了在污染严重地区进行空气质量监测和控制的紧迫性。
