Li Xiaoyong, Shen Peng, Lin Hongbo, Yu Zhebin, Chen Kun, Wang Jianbing
Department of Health Education and Chronic Disease Control, Ningbo Yinzhou District Center for Disease Control and Prevention, Ningbo 315040, Zhejiang Province, China.
School of Public Health, Zhejiang University School of Medicine, Hangzhou 310058, China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2018 May 25;47(2):163-168. doi: 10.3785/j.issn.1008-9292.2018.04.09.
To investigate the prevalence and risk factors of diabetic nephropathy in Ningbo Yinzhou district.
Nephropathy screening was conducted among patients with type 2 diabetes mellitus (T2DM) registered in Ningbo Yinzhou district. Demographic information, clinical examination information, diabetes complications and behavioral risk factors of enrolled patients were collected. Logistic regression model was used to identify possible risk factors for the occurrence of diabetic nephropathy.
Among 10 604 T2DM patients included in this study, there were 3744 cases of diabetic nephropathy(35.31%). Univariate analysis showed that gender, age, education level, diabetes duration, glycemic control, hypertension, stroke, smoking and waist circumference were associated with diabetic nephropathy (<0.05 or <0.01). Multivariate logistic regression analysis showed that male, elders, long diabetes duration, hypertension and smoking were independent risk factors of diabetic nephropathy (<0.05 or <0.01).
sDiabetic nephropathy is of high prevalence in T2DM patients. Male patients, elders, and those with long diabetes duration, hypertension and smoking habits are more likely to have diabetic nephropathy.
调查宁波市鄞州区糖尿病肾病的患病率及危险因素。
对宁波市鄞州区登记的2型糖尿病（T2DM）患者进行肾病筛查。收集纳入患者的人口统计学信息、临床检查信息、糖尿病并发症及行为危险因素。采用Logistic回归模型确定糖尿病肾病发生的可能危险因素。
本研究纳入的10604例T2DM患者中，糖尿病肾病患者3744例（35.31%）。单因素分析显示，性别、年龄、教育程度、糖尿病病程、血糖控制、高血压、中风、吸烟和腰围与糖尿病肾病相关（P<0.05或P<0.01）。多因素Logistic回归分析显示，男性、老年人、糖尿病病程长、高血压和吸烟是糖尿病肾病的独立危险因素（P<0.05或P<0.01）。
T2DM患者中糖尿病肾病患病率较高。男性患者、老年人以及糖尿病病程长、有高血压和吸烟习惯的患者更易患糖尿病肾病。
