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儿科肺部磁共振成像的结构和功能——从新生儿到青年。

Structural and Functional Pulmonary Magnetic Resonance Imaging in Pediatrics-From the Neonate to the Young Adult.

机构信息

Center for Pulmonary Imaging Research, Division of Pulmonary Medicine and Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229.

Center for Pulmonary Imaging Research, Division of Pulmonary Medicine and Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229; Departments of Radiology and Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229.

出版信息

Acad Radiol. 2019 Mar;26(3):424-430. doi: 10.1016/j.acra.2018.08.006. Epub 2018 Sep 15.

DOI:10.1016/j.acra.2018.08.006
PMID:30228041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6535094/
Abstract

The clinical imaging modalities available to investigate pediatric pulmonary conditions such as bronchopulmonary dysplasia, cystic fibrosis, and asthma are limited primarily to chest x-ray radiograph and computed tomography. As the challenges that historically limited the application of magnetic resonance imaging (MRI) to the lung have been overcome, its clinical potential has greatly expanded. In this review article, recent advances in pulmonary MRI including ultrashort echo time and hyperpolarized-gas MRI techniques are discussed with an emphasis on pediatric research and translational applications.

摘要

用于研究小儿肺部疾病(如支气管肺发育不良、囊性纤维化和哮喘)的临床影像学方法主要限于胸部 X 射线摄影和计算机断层扫描。随着历史上限制磁共振成像(MRI)在肺部应用的挑战得到克服,其临床潜力大大扩展。在这篇综述文章中,讨论了包括超短回波时间和超极化气体 MRI 技术在内的肺部 MRI 的最新进展,重点是儿科研究和转化应用。

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本文引用的文献

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Neonatal Pulmonary Magnetic Resonance Imaging of Bronchopulmonary Dysplasia Predicts Short-Term Clinical Outcomes.新生儿肺部磁共振成像预测支气管肺发育不良的短期临床结局。
Am J Respir Crit Care Med. 2018 Nov 15;198(10):1302-1311. doi: 10.1164/rccm.201711-2287OC.
2
Pulmonary ventilation imaging in asthma and cystic fibrosis using oxygen-enhanced 3D radial ultrashort echo time MRI.使用氧增强 3D 径向超短回波时间 MRI 进行哮喘和囊性纤维化的肺部通气成像。
J Magn Reson Imaging. 2018 May;47(5):1287-1297. doi: 10.1002/jmri.25877. Epub 2017 Oct 31.
3
Evaluation of Neonatal Lung Volume Growth by Pulmonary Magnetic Resonance Imaging in Patients with Congenital Diaphragmatic Hernia.先天性膈疝患者肺磁共振成像评估新生儿肺容积增长情况
J Pediatr. 2017 Sep;188:96-102.e1. doi: 10.1016/j.jpeds.2017.06.002. Epub 2017 Jun 29.
4
Hyperpolarized helium-3 magnetic resonance lung imaging of non-sedated infants and young children: a proof-of-concept study.非镇静婴幼儿的超极化氦-3磁共振肺部成像:一项概念验证研究。
Clin Imaging. 2017 Sep-Oct;45:105-110. doi: 10.1016/j.clinimag.2017.04.004. Epub 2017 May 10.
5
Neonatal imaging using an on-site small footprint MR scanner.使用现场小型磁共振扫描仪进行新生儿成像。
Pediatr Radiol. 2017 Jul;47(8):1001-1011. doi: 10.1007/s00247-017-3855-4. Epub 2017 May 3.
6
Correlation of Lung Clearance Index with Hyperpolarized Xe Magnetic Resonance Imaging in Pediatric Subjects with Cystic Fibrosis.肺清除指数与超极化氙磁共振成像在囊性纤维化儿科患者中的相关性
Am J Respir Crit Care Med. 2017 Oct 15;196(8):1073-1075. doi: 10.1164/rccm.201611-2228LE.
7
Quantification of neonatal lung parenchymal density via ultrashort echo time MRI with comparison to CT.利用超短回波时间 MRI 对新生儿肺实质密度进行定量分析,并与 CT 进行比较。
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Comparison of Lung Clearance Index and Magnetic Resonance Imaging for Assessment of Lung Disease in Children with Cystic Fibrosis.肺清除指数与磁共振成像在儿童囊性纤维化肺部疾病评估中的比较。
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Ann Am Thorac Soc. 2016 Nov;13(11):1923-1931. doi: 10.1513/AnnalsATS.201603-203OC.