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本文引用的文献

1
Pathophysiology of gastroesophageal reflux disease: new understanding in a new era.胃食管反流病的病理生理学:新时代的新认识
Neurogastroenterol Motil. 2015 Sep;27(9):1202-13. doi: 10.1111/nmo.12611. Epub 2015 Jun 5.
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Risk factors for gastroesophageal reflux disease: the role of diet.胃食管反流病的危险因素:饮食的作用。
Prz Gastroenterol. 2014;9(5):297-301. doi: 10.5114/pg.2014.46166. Epub 2014 Oct 19.
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Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review.胃食管反流病的流行病学更新:系统评价。
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Guidelines for the diagnosis and management of gastroesophageal reflux disease.胃食管反流病诊断和管理指南
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5
Diagnostic accuracy of age and alarm symptoms for upper GI malignancy in patients with dyspepsia in a GI clinic: a 7-year cross-sectional study.上消化道恶性肿瘤在胃肠科消化不良患者中年龄和报警症状的诊断准确性:一项 7 年的横断面研究。
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Effect of bed head elevation during sleep in symptomatic patients of nocturnal gastroesophageal reflux.睡眠时床头抬高对夜间胃食管反流症状患者的影响。
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7
Globus sensation and increased upper esophageal sphincter pressure with distal esophageal acid perfusion.食管远端酸灌注时出现球塞感和食管上括约肌压力增高。
Eur Arch Otorhinolaryngol. 2010 May;267(5):737-41. doi: 10.1007/s00405-009-1134-1. Epub 2009 Nov 1.
8
Efficacy of esophageal impedance/pH monitoring in patients with refractory gastroesophageal reflux disease, on and off therapy.食管阻抗/pH监测在难治性胃食管反流病患者治疗期间及停药后疗效的研究
Clin Gastroenterol Hepatol. 2009 Jul;7(7):743-8. doi: 10.1016/j.cgh.2009.02.022. Epub 2009 Mar 9.
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Barrett's oesophagus.巴雷特食管
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Proton pump inhibitors and bone fractures?质子泵抑制剂与骨折?
Am J Gastroenterol. 2009 Mar;104 Suppl 2:S21-6. doi: 10.1038/ajg.2009.48.

胃食管反流病(GERD)。

Gastroesophageal Reflux Disease (GERD).

作者信息

Clarrett Danisa M, Hachem Christine

机构信息

Danisa M. Clarrett, MD, MS, is a Fellow in the Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, Mo.

Christine Hachem, MD, is an Associate Professor of Internal Medicine, Division of Gastroenterology and Hepatology, Saint Louis University School of Medicine, St. Louis, Mo.

出版信息

Mo Med. 2018 May-Jun;115(3):214-218.

PMID:30228725
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6140167/
Abstract

Gastroesophageal reflux disease (GERD) is a common clinical problem, affecting millions of people worldwide. Patients are recognized by both classic and atypical symptoms. Acid suppressive therapy provides symptomatic relief and prevents complications in many individuals with GERD. Advances in diagnostic and therapeutic modalities have improved our ability to identify and manage disease complications. Here, we discuss the pathophysiology and effects of GERD, and provide information on the clinical approach to this common disorder.

摘要

胃食管反流病(GERD)是一个常见的临床问题,影响着全球数百万人。患者可通过典型症状和非典型症状来识别。抑酸治疗可为许多胃食管反流病患者缓解症状并预防并发症。诊断和治疗方式的进步提高了我们识别和处理疾病并发症的能力。在此,我们讨论胃食管反流病的病理生理学和影响,并提供有关这一常见病症临床处理方法的信息。