Temesgen Tegegne Gobezie, Teshome Berhanu, Njogu Peter
Addis Ababa University, College of Health Sciences, School of Pharmacy, Department of Pharmacology and Clinical Pharmacy, Ethiopia.
Ambo University, College of Medicine and Health Sciences, Department of Pharmacy, Ethiopia.
Stroke Res Treat. 2018 Aug 28;2018:8079578. doi: 10.1155/2018/8079578. eCollection 2018.
The 2013 Global Burden of Disease report indicated that 80% of stroke deaths occur in low- and middle-income regions. Although stroke has been consistently reported as one of the three leading causes of morbidity and mortality in the past years in Ethiopia, there is a paucity of data regarding treatment outcomes of stroke if sufficient. Hence, the present study aimed to assess patterns of treatment outcomes and associated factors among hospitalized stroke patients at Shashemene Referral Hospital.
A retrospective cross-sectional study was conducted at the medical ward of Shashemene Referral Hospital. A total of 73 hospitalized stroke patients during the period 2012-2017 were included in the study. Demographic characteristics, risk factors, and stroke types and their hospital outcomes were reviewed from the medical records of the patients. The data were entered and analyzed using SPSS version 16.0. Descriptive statistics such as percent and frequency were used to summarize patients' characteristics. Binary logistic regression was used to investigate the potential predictors of treatment outcome. A p-value ≤0.05 was considered statistically significant.
Ischemic stroke was the most common type of stroke (65.8%) diagnosed in our setting. Hypertension (52.05%) was the common comorbid condition. More than half (54.79%) of the stroke patients improved on treatment. Dyslipidemics were prescribed to 68.49% of patients and the most popular antiplatelet was aspirin, which was prescribed to 61.64% of the study participants. Age, sex, type of stroke, and type of comorbidity were not significant factors of stroke treatment outcome.
Ischemic stroke was the most common type of stroke diagnosed among the study participants while aspirin and statins were the most frequently used drugs in the management of stroke. Approximately 50% of hospitalized stroke patients had good treatment outcome and none of the investigated variables were significantly associated with the treatment outcomes.
《2013年全球疾病负担报告》指出,80%的中风死亡发生在低收入和中等收入地区。尽管在过去几年中,中风一直被报告为埃塞俄比亚发病和死亡的三大主要原因之一,但关于中风治疗结果的数据(如果足够的话)却很匮乏。因此,本研究旨在评估沙舍梅内转诊医院住院中风患者的治疗结果模式及相关因素。
在沙舍梅内转诊医院的内科病房进行了一项回顾性横断面研究。研究纳入了2012年至2017年期间共73名住院中风患者。从患者的病历中回顾了人口统计学特征、危险因素、中风类型及其住院结局。使用SPSS 16.0版本输入和分析数据。使用百分比和频率等描述性统计方法来总结患者的特征。二元逻辑回归用于研究治疗结果的潜在预测因素。p值≤0.05被认为具有统计学意义。
缺血性中风是我们所研究环境中最常见的中风类型(65.8%)。高血压(52.05%)是常见的合并症。超过一半(54.79%)的中风患者治疗后病情好转。68.49%的患者使用了调脂药,最常用的抗血小板药物是阿司匹林,61.64%的研究参与者使用了该药物。年龄、性别、中风类型和合并症类型不是中风治疗结果的显著因素。
缺血性中风是研究参与者中诊断出的最常见中风类型,而阿司匹林和他汀类药物是中风管理中最常用的药物。约50%的住院中风患者治疗效果良好,所研究的变量均与治疗结果无显著关联。