College of Chemistry Engineering, Northeast Electric Power University, Jilin 132012, China.
Org Biomol Chem. 2018 Oct 3;16(38):6865-6869. doi: 10.1039/c8ob01938j.
A three-component cascade reaction is described that provides concise access to 6H-benzo[c]chromenes via Rh(iii)-catalyzed annulation of aryl ketone O-acyloximes, quinones and acetone. Acetone acts as a co-solvent and as a reactant. This reaction shows high efficiency, atom- and step-economy, good substrate scope, excellent functional group compatibility and gives the products in good yields.
描述了一种三组分级联反应，通过 Rh(iii)催化芳基酮 O-酰氧基肟、醌和丙酮的环化反应，简洁地合成了 6H-苯并[c]色烯。丙酮作为共溶剂和反应物。该反应具有高效、原子经济性和步骤经济性、良好的底物范围、优异的官能团兼容性，并且以良好的收率得到产物。
