Aldstadt J H, Allen M J, Johnson P
Comp Biochem Physiol B. 1986;85(2):355-63. doi: 10.1016/0305-0491(86)90012-x.
The desmin-specific calpain I from chicken gizzard smooth muscle is a dimer of 83 and 35 kDalton subunits. A monoclonal antibody to the large subunit did not cross-react with chicken gizzard and hamster skeletal muscle calpain II, but it did recognize hamster skeletal muscle desmin-specific calpain I and the denatured calpain II from chicken gizzard smooth muscle. These results indicate that different desmin-specific calpains have similar large subunits which differ significantly from the large subunit of calpain II in the same tissue.
来自鸡肫平滑肌的结蛋白特异性钙蛋白酶Ⅰ是由83千道尔顿和35千道尔顿亚基组成的二聚体。针对大亚基的单克隆抗体与鸡肫和仓鼠骨骼肌的钙蛋白酶Ⅱ无交叉反应，但它能识别仓鼠骨骼肌结蛋白特异性钙蛋白酶Ⅰ以及鸡肫平滑肌的变性钙蛋白酶Ⅱ。这些结果表明，不同的结蛋白特异性钙蛋白酶具有相似的大亚基，这些大亚基与同一组织中钙蛋白酶Ⅱ的大亚基有显著差异。
