人类嗜T淋巴细胞病毒I型/II型（HTLV-I/II）的pX基因与小鼠白细胞介素-3基因之间的序列同源性。
A sequence homology between the pX genes of HTLV-I/II and the murine IL-3 gene.
作者信息
Gojobori T, Aota S, Inoue T, Shimotohno K
出版信息
FEBS Lett. 1986 Nov 24;208(2):231-5. doi: 10.1016/0014-5793(86)81023-7.
Searching the protein sequence database for amino acid sequences homologous to the x-lor sequence in the pX region of human T-cell leukemia virus types I and II (HTLV-I/II), we found that there is a region of 38 amino acids where the murine interleukin 3 (IL-3) sequence has a 40% homology with the x-lor sequence. A statistical analysis shows that this homology is highly significant with a probability of 1.57 X 10(-10). The biological implication of this homology is discussed.
在蛋白质序列数据库中搜索与人类I型和II型T细胞白血病病毒（HTLV-I/II）pX区域的x-lor序列同源的氨基酸序列时，我们发现小鼠白细胞介素3（IL-3）序列有一个38个氨基酸的区域与x-lor序列具有40%的同源性。统计分析表明，这种同源性非常显著，概率为1.57×10^(-10)。本文讨论了这种同源性的生物学意义。
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