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Patient Comprehension of Medication Guides for Asthma and Chronic Obstructive Pulmonary Disease Medications.

作者信息

DiSantostefano Rachael L, Beck Melissa, Yeakey Anne M, Raphiou Ibrahim, Stempel David A

机构信息

1 GlaxoSmithKline, Research Triangle Park, NC, USA.

2 Regulated Healthcare Market Research, Concentrics Research, Indianapolis, IN, USA.

出版信息

Ther Innov Regul Sci. 2014 Sep;48(5):574-582. doi: 10.1177/2168479014524407.

Abstract

PURPOSE

This study assessed patients' comprehension of the Advair and Serevent medication guides (MGs) and MG reading behaviors with the goal to improve risk communication.

METHODS

After reading their assigned MGs, 452 adults with asthma or chronic obstructive pulmonary disease participated in structured interviews to assess comprehension of safety risks in the Advair MG (asthma, n = 150; chronic obstructive pulmonary disease, n = 153) and Serevent MG (asthma, n = 149). Generalized estimating equations for correlated binary data were used to identify factors associated with correct responses.

RESULTS

For 10 of 12 individual risk questions, ≥75% of patients reported correct responses. After adjusting for patient characteristics, health literacy was significantly associated with correct responses (odds ratio = 1.03, 95% confidence interval = 1.02-1.05 per 1-point increase in the Rapid Estimate of Adult Literacy in Medicine). MG reading behaviors were inconsistent, with many patients reading MGs only once (40%) despite multiple prescriptions.

CONCLUSIONS

Comprehension of safety risks in the Advair and Serevent MGs was adequate for most patients in the study but decreased with health literacy. Initiatives to improve patient-directed risk communication should consider health literacy and reasons for inconsistent reading behaviors.

摘要

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