一名免疫功能正常的患者中，罕见的弥漫性颅内曲霉菌病伪装成颅底脑膜瘤的病例。

A rare case of diffuse intracranial aspergillosis masquerading as skull base meningioma in an immunocompetent patient.

作者信息

Pant Ishita, Chaturvedi Sujata, Singh Avneesh Kumar, Singh Gurbachan, Tiwari Sadhna

出版信息

Clin Neuropathol. 2019 Jan/Feb;38(1):23-27. doi: 10.5414/NP301106.

Abstract

Intracranial aspergillosis is rare in immunocompetent patients. Its presentation is subtle, often without any diagnostic characteristics, and is frequently mistaken for tuberculous meningitis, pyogenic abscess, or a space-occupying lesion. The authors report a case of diffuse intracranial aspergillosis, in an immunocompetent 34-year-old male, that mimicked a meningioma on preoperative imaging. The origin, clinical course, radiological features, histopathological findings, and surgical treatment are discussed based on review of literature. .

摘要

颅内曲霉菌病在免疫功能正常的患者中较为罕见。其表现隐匿，通常没有任何诊断特征，常被误诊为结核性脑膜炎、化脓性脓肿或占位性病变。作者报告了一例34岁免疫功能正常男性的弥漫性颅内曲霉菌病病例，该病例在术前影像学上酷似脑膜瘤。本文在回顾文献的基础上，讨论了其发病原因、临床过程、影像学特征、组织病理学表现及外科治疗。