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[神经与神经电模型(ENM)中的半兴奋状态(作者译)]

[Semi-excitation in nerve and electric nerve model (ENM) (author's transl)].

作者信息

Matumoto M, Hanba M

出版信息

Nihon Seirigaku Zasshi. 1977;39(4):69-77.

PMID:302336
Abstract

The "semi-excitation" is an excitation (like phenomenon) found by the authors, first in ENM and then in nerve during observation of the action potential and impedance decrease associated with excitation. The phenomenon was further investigated in relation to the action potential and impedance decrease (for AC of 13 kHz) of the stimulated site on the sciatic nerve and ENM. The nature of the phenomenon was the following. 1. The configuration of the action potential and impedance decrease were almost the same as that of the (complete) excitation, but the durations of the potential change (plateau) and impedance decrease depended on entirely to the duration of stimulating current. 2. Submaximum amplitude of action potential and impedance decrease were graded by the intensity of the stimulating current, but the threshold of this excitation was found. 3. During or after the semi-excitation, absolute or relative refractory period was not found. 4. Both in nerve and ENM, transition from complete excitation to semi-excitation or vice versa was observed. 5. Semi-excitation was found to occurr in the state of reduced membrane potential of the nerve and ENM.

摘要

“半兴奋”是作者首先在运动终板,然后在神经中观察与兴奋相关的动作电位和阻抗降低时发现的一种兴奋(类兴奋现象)。针对坐骨神经和运动终板上受刺激部位的动作电位和阻抗降低(对于13kHz的交流电),对该现象进行了进一步研究。该现象的本质如下:1. 动作电位和阻抗降低的形态与(完全)兴奋的几乎相同,但电位变化(平台期)和阻抗降低的持续时间完全取决于刺激电流的持续时间。2. 动作电位和阻抗降低的亚最大幅度随刺激电流强度分级,但发现了这种兴奋的阈值。3. 在半兴奋期间或之后,未发现绝对或相对不应期。4. 在神经和运动终板中,均观察到从完全兴奋到半兴奋或反之的转变。5. 发现半兴奋发生在神经和运动终板膜电位降低的状态下。

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