Serag Hosam, Bang Shirley, Almallah Y Zaki
Department of Urology, Queen Elizabeth Hospital Birmingham-University Hospital Birmingham, Birmingham, UK Correspondence: Hosam Serag Department of Urology, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2GW, UK,
Res Rep Urol. 2018 Sep 4;10:63-68. doi: 10.2147/RRU.S172252. eCollection 2018.
To report a real-time contemporary practice and outcome of artificial urinary sphincter (AUS) in patients with postradical prostatectomy urinary incontinence (PPI) in the UK.
A retrospective observational study of patients who underwent AUS implantation (AMS 800) from 2007 to 2013. Data were collected on patients' demographics, infection and erosion rate, mechanical failure, reoperation, and continence rates. The study strictly included patients with postradical PPI only. Minimum follow-up was 15 months.
Eighty-four AUSs were implanted over a period of 6 years. Patients' age ranged between 51 and 78 (median 69, mean 69.25) years. Median follow-up was 37 months, mean 39 months, and range 15-92 months. Among the 83 follow-up patients, 38.5% (32/83) reported that they were completely dry with no pads; 42.2% (35/83) of patients were socially continent (using 1 pad/day) and 19.3% (16/83) using ≥2 pads/day. One patient was lost to follow-up. Reoperation rate was 13.25% (11/83), including nine mechanical failures (10.8%). Two implant infections (2.4%) required explantation, out of which one had erosion (1.2%). Bladder overactivity developed in 6% of patients. Of the 83, 15 (18%) had pelvic radiotherapy.
The implantation of AUS in patients with post-PPI has lower complications and reoperation rates than historical impression painted in the literature. This can be beneficial in counseling as well as during the education process of patients going through the decision process for prostate cancer treatment. Furthermore, these figures can add to our quest to increase the awareness of the success of anti-incontinence surgery among patients.
报告英国根治性前列腺切除术后尿失禁(PPI)患者人工尿道括约肌(AUS)的当代实时应用情况及结果。
对2007年至2013年接受AUS植入术(AMS 800)的患者进行回顾性观察研究。收集患者的人口统计学数据、感染和侵蚀率、机械故障、再次手术情况及控尿率。该研究严格仅纳入根治性PPI患者。最短随访时间为15个月。
在6年时间里共植入84例AUS。患者年龄在51至78岁之间(中位数69岁,平均69.25岁)。中位随访时间为37个月,平均39个月,范围为15至92个月。在83例接受随访的患者中,38.5%(32/83)报告完全干爽无需使用尿垫;42.2%(35/83)的患者社交场合可控尿(每天使用1片尿垫),19.3%(16/83)的患者每天使用≥2片尿垫。1例患者失访。再次手术率为13.25%(11/83),其中9例为机械故障(10.8%)。2例植入感染(2.4%)需要取出装置,其中1例发生侵蚀(1.2%)。6%的患者出现膀胱过度活动症。83例患者中,15例(18%)接受过盆腔放疗。
与文献中以往的印象相比,PPI患者植入AUS的并发症和再次手术率更低。这在患者咨询以及前列腺癌治疗决策过程中的教育过程中可能有益。此外,这些数据有助于提高患者对抗尿失禁手术成功率的认识。