Osol G, Halpern W
J Hypertens Suppl. 1986 Oct;4(3):S517-8.
Using an in vitro pressurized technique, we measured the myogenic pressure range and degree of myogenic activity in posterior cerebral arteries from stroke-prone spontaneously hypertensive rats (SHRSP) and rats of the same strain maintained by antihypertensive therapy. Treatment lowered the upper myogenic pressure limit and increased the strength of the myogenic response to levels comparable with those previously found in normotensive (Wistar-Kyoto, WKY) rats, suggesting that blood pressure history is the primary determinant of myogenic properties in the cerebral circulation.
利用体外加压技术，我们测量了易中风自发性高血压大鼠（SHRSP）以及接受降压治疗的同品系大鼠大脑后动脉的肌源性压力范围和肌源性活动程度。治疗降低了肌源性压力上限，并增强了肌源性反应强度，使其达到与之前在正常血压（Wistar-Kyoto，WKY）大鼠中发现的水平相当，这表明血压病史是脑循环中肌源性特性的主要决定因素。
