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[心肌梗死患者中性粒细胞的组织化学研究]

[Histochemical studies of neutrophils in myocardial infarct patients].

作者信息

Slovin'ski S, Moshchyn'ski P

出版信息

Kardiologiia. 1986 Sep;26(9):25-8.

PMID:3023734
Abstract

Cytochemical assays of neutrophil acid phosphatase, beta-glucuronidase, N-acetyl-beta-D-glycosamidase (NAG), myeloperoxidase activities, and the Sudan black B test, were carried out in 25 patients with myocardial infarction. Leucocytosis seen in the early days of infarction was associated with increased proportion of neutrophils characterized by high activities of the enzymes in question and enhanced reaction with Sudan black B. Neutrophilosis of the early myocardial infarction may result from the activity of the marginal cell fraction. The fact that increased myeloperoxidase activity and the enhanced response to Sudan black B persist through 14 days of the disease, coupled with a rise in neutrophil NAG activity on day 14, expands possibilities of myocardial infarction diagnosis.

摘要

对25例心肌梗死患者进行了中性粒细胞酸性磷酸酶、β-葡萄糖醛酸酶、N-乙酰-β-D-氨基葡萄糖苷酶(NAG)、髓过氧化物酶活性的细胞化学测定以及苏丹黑B试验。梗死早期出现的白细胞增多与中性粒细胞比例增加有关,这些中性粒细胞的特征是上述酶活性高,且与苏丹黑B的反应增强。早期心肌梗死时的中性粒细胞增多可能源于边缘细胞部分的活性。髓过氧化物酶活性增加以及对苏丹黑B的反应增强在疾病的14天内持续存在,再加上第14天中性粒细胞NAG活性升高,这扩大了心肌梗死诊断的可能性。

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