Division of Newborn Medicine, Tufts Medical Center, Boston, MA, USA.
Cape Cod Health, Hyannis, MA, USA.
J Perinatol. 2018 Dec;38(12):1651-1656. doi: 10.1038/s41372-018-0230-8. Epub 2018 Sep 20.
To compare length of hospital stay (LOS), LOS due to neonatal abstinence syndrome (NAS), and duration of pharmacologic treatment in community or academic settings.
One hundred-two infants exposed to opioids in utero at two community hospitals were compared to 256 from eight academic centers. All infants were managed with non-pharmacologic care followed by similar pharmacologic treatment options.
Two hundred-twelve infants received pharmacologic treatment for NAS. Mean LOS (24.7 ± 8.5 vs. 24.5 ± 11.3 days), LOS due to NAS (24.0 ± 8.2 vs. 23.3 ± 9.2 days), and duration of NAS treatment (19.3 ± 8.0 vs. 18.9 ± 9.2 days) were similar in community compared to academic medical centers.
No significant differences were found in infants managed in the community compared to academic care settings. These findings support caring for opioid-exposed infants in both community and academic settings with the use of standardized care protocols.
比较社区或学术环境中新生儿戒断综合征（NAS）的住院时间（LOS）、LOS 以及药物治疗持续时间。
将两家社区医院的 102 名宫内暴露于阿片类药物的婴儿与 8 家学术中心的 256 名婴儿进行比较。所有婴儿均接受非药物治疗，然后采用类似的药物治疗方案。
212 名婴儿接受了 NAS 的药物治疗。社区医疗中心和学术医疗中心的 LOS（24.7±8.5 天 vs. 24.5±11.3 天）、NAS 相关 LOS（24.0±8.2 天 vs. 23.3±9.2 天）和 NAS 治疗持续时间（19.3±8.0 天 vs. 18.9±9.2 天）相似。
在社区管理的婴儿与学术护理环境中，未发现明显差异。这些发现支持在社区和学术环境中使用标准化护理方案来治疗阿片类药物暴露的婴儿。
