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一项评估在州立医疗保健体系中患有唐氏综合征儿童的母亲抑郁状况的初步研究。

A pilot study evaluating depression in mothers with children diagnosed with Down syndrome in state health care.

机构信息

Division of Human Genetics, School of Pathology, Faculty of Health Sciences, The University of the Witwatersrand, Johannesburg, South Africa.

Clinical Genetic Unit, National Health Laboratory Service, Braamfontein, Johannesburg, South Africa.

出版信息

J Intellect Disabil Res. 2018 Nov;62(11):952-961. doi: 10.1111/jir.12549. Epub 2018 Sep 19.

Abstract

BACKGROUND

Parenting a child who has an intellectual disability has been shown to increase the risk for developing depression. The purpose of this study was to screen for depression and to determine if there is an association between depressive symptoms and certain sociodemographic factors in mothers with a child diagnosed with Down syndrome in state health care facilities in Johannesburg.

METHODS

The study included 30 biological mothers of children between 6 months and 3 years diagnosed with Down syndrome postnatally. The Edinburgh Postnatal Depression Scale (EPDS) was used to assess depression in participants. A 10-item sociodemographic questionnaire was concurrently administered. Data analysis was conducted using descriptive and inferential statistical analysis.

RESULTS

The 30 mothers had a mean EPDS score of 9.1 (SD = 5.89) with scores ranging between 0 and 26. Eight mothers (26.7%) screened positive for depression with an EPDS score of 13 or greater. A statistically significant association was found between an HIV-positive status and mothers who had an EPDS score of 13 or greater (P = 0.01). No significant association between depression and various other sociodemographic factors was identified.

CONCLUSIONS

Mothers with a child diagnosed with Down syndrome may be vulnerable to developing depression. A significant association was found between a positive HIV status and symptoms of depression, in mothers with a child diagnosed with Down syndrome. This study indicates the need for further investigations assessing the causes and risk factors resulting in postnatal depression in mothers with a child diagnosed with Down syndrome.

摘要

背景

育儿有智力障碍的孩子会增加患抑郁症的风险。本研究的目的是筛查抑郁症,并确定在约翰内斯堡州立医疗机构中,患有唐氏综合征的儿童的母亲中,抑郁症状与某些社会人口因素之间是否存在关联。

方法

本研究纳入了 30 名患有唐氏综合征的 6 个月至 3 岁儿童的亲生母亲。采用爱丁堡产后抑郁量表(EPDS)评估参与者的抑郁情况。同时进行了一个包含 10 个项目的社会人口学问卷。采用描述性和推断性统计分析进行数据分析。

结果

30 位母亲的 EPDS 平均得分为 9.1(SD=5.89),得分范围为 0 至 26。8 位母亲(26.7%)筛查出抑郁,EPDS 得分≥13。HIV 阳性与 EPDS 得分≥13 的母亲之间存在统计学显著关联(P=0.01)。未发现抑郁与其他各种社会人口学因素之间存在显著关联。

结论

被诊断患有唐氏综合征的儿童的母亲可能容易患上抑郁症。HIV 阳性与唐氏综合征儿童的母亲的抑郁症状之间存在显著关联。本研究表明,需要进一步调查评估导致唐氏综合征儿童的母亲产后抑郁的原因和风险因素。

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