Moukram K H, Haitami S, Yahya I Ben
Odontostomatol Trop. 2016 Sep;39(155):27-31.
First described by Philipsen in 1956, the odontogenic keratocyst is characterized by a large squamous keratinization of its border, an aggressive growth and a high recurrent rate. It is now designated by the World Health Organization as a Keratocystic Odontogenic Tumor (KOT). Clinically, the KOT is manifested by an asymptomatic growth. Radiographically, it appears as a well-defined unilocular or multilocular osteolytic lesion. The diagnostic approach is based on a combined analysis of the medical history, the clinical appearance and the radiographic appearance. The diagnosis may be confirmed by the anatomical pathology report. Finally, treatment consists of surgical excision and follow up is characterized by a high rate of recurrence. The authors report a case of keratocystic odontogenic tumor of the mandible and review the various diagnoses, therapeutics and follow up aspects of this type of tumors.
牙源性角化囊肿于1956年由菲利普森首次描述,其特征为边界处大量鳞状角化、生长侵袭性强且复发率高。现在世界卫生组织将其命名为角化囊性牙源性肿瘤(KOT)。临床上,KOT表现为无症状性生长。在影像学上,它表现为边界清晰的单房或多房溶骨性病变。诊断方法基于病史、临床表现和影像学表现的综合分析。诊断可通过解剖病理学报告得以证实。最后,治疗包括手术切除,且随访显示复发率高。作者报告了一例下颌骨角化囊性牙源性肿瘤病例,并回顾了这类肿瘤的各种诊断、治疗及随访方面的情况。