Guo Averill, Poneros John M
Columbia University Medical Center, 161 Fort Washington Avenue, Suite 852, New York, NY 10032, USA.
Columbia University Medical Center, 161 Fort Washington Avenue, Suite 852, New York, NY 10032, USA.
Gastrointest Endosc Clin N Am. 2018 Oct;28(4):455-476. doi: 10.1016/j.giec.2018.05.001. Epub 2018 Aug 1.
Patients with recurrent acute pancreatitis (RAP) have few treatment options available to them to manage their symptoms or prevent progression to chronic pancreatitis. At present, endotherapy is typically pursued as a means to achieve symptom remission and reduce rates of recurrence, hospitalization, abdominal pain, narcotic use, and surgical intervention. However, evidence that endotherapy effectively alters the natural history of disease remains limited. This article reviews the recent literature on the efficacy of endoscopic intervention in the treatment RAP with a focus on high-quality prospective randomized controlled studies. Additional studies are needed to corroborate these findings.
复发性急性胰腺炎(RAP)患者在控制症状或预防进展为慢性胰腺炎方面几乎没有可用的治疗选择。目前,内镜治疗通常被作为实现症状缓解、降低复发率、住院率、腹痛、麻醉药物使用及手术干预的一种手段。然而,内镜治疗能有效改变疾病自然病程的证据仍然有限。本文回顾了近期关于内镜干预治疗RAP疗效的文献,重点关注高质量的前瞻性随机对照研究。需要更多研究来证实这些发现。